Skip to content

Basophils and Mast Cells, Cerebrospinal Fluid — Number per Volume

Published: August 9, 2026Updated: August 17, 2026

A cerebrospinal fluid cell test that measures basophils and mast cells to help evaluate inflammation, allergy-related reactions, or infection.

Quick summary

["This is a specialized cerebrospinal fluid cell count used to assess possible inflammatory, allergic, or infectious conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
69913-2
Short code
Basophils/Masts NFr CSF
Synonyms
Basophils/Masts NFr CSF
Category
liver
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What is this test?

This test measures the number of basophils and mast cells in cerebrospinal fluid (CSF), the fluid surrounding the brain and spinal cord. These cells are part of the immune system and are usually measured as part of a broader CSF differential.

Why might I need this test?

The test may be included when CSF is being evaluated for infection, inflammation, or an immune-related condition. Results are interpreted together with the rest of the CSF analysis rather than by themselves.

How is the test performed?

CSF is usually collected by lumbar puncture, also called a spinal tap. A laboratory then counts the basophils and mast cells in the specimen and reports their concentration.

How do I prepare for the test?

A lumbar puncture is performed by a trained clinician and usually requires no special preparation beyond following the clinician's instructions. You may be asked to lie still during the procedure and to tell the clinician about bleeding problems, medicines, or allergies.

Reference range

Adult: 10-40 U/LN/A

Specimen: csf

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CSF Basophils and Mast Cells

Frequently asked questions

Does this test require a lumbar puncture?
Usually, yes. Cerebrospinal fluid is most commonly collected through a lumbar puncture, although it can occasionally be obtained from another location if clinically necessary.
Are elevated basophils or mast cells diagnostic of an allergy?
No. Increased cells may suggest an allergic or immune-related process, but they can also occur with infection or inflammation and are not diagnostic by themselves.
Why are other cerebrospinal fluid tests important?
Cell counts, protein, glucose, and microbiology results provide context for interpreting basophils and mast cells. Your clinician should interpret the complete CSF panel along with your symptoms and medical history.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy