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Basophils and Mast Cells — Cell Count

Published: August 9, 2026Updated: August 17, 2026

A laboratory count of basophils and mast cells, related immune cells that can be reported as a number or fraction in the tested specimen.

Quick summary

["This test measures the amount of basophils and mast cells and may help evaluate allergic or inflammatory conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
69916-5
Short code
Basophils/Masts NFr Snv
Synonyms
Basophils/Masts NFr Snv
Category
liver
Sample
fluid
Container
Sterile tube
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What is this test?

This test counts basophils and mast cells, which are related white blood cells involved in immune and inflammatory responses. Depending on the specimen and laboratory method, the result may be reported as a number per volume or as a fraction of all counted cells.

Why might I need this test?

This test may be ordered as part of a blood or body-fluid cell count and differential. It can help a clinician evaluate an unexplained increase in white blood cells or investigate symptoms that may be related to allergy, inflammation, infection, or medication effects.

How is the test performed?

A laboratory professional examines the specimen with a counting method and determines the number or proportion of basophils and mast cells. Some laboratory analyzers group these closely related cells together, so the exact reporting method can vary.

How do I prepare for the test?

If the test uses a blood sample, fasting is usually not required unless your clinician gives different instructions. For other specimens, follow the specific collection and preparation directions provided by your healthcare team.

Reference range

Adult: 10-40 U/LN/A

Specimen: fluid

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An increased result may occur with allergic conditions, inflammation, infection, certain medications, or other causes of white blood cell activation. A decreased or very low result is often less clinically significant on its own and must be interpreted with the rest of the blood count. The specimen type, symptoms, medications, and laboratory method should all be considered when reviewing the result.

Short name

Basophils/Mast cells

Frequently asked questions

What are basophils and mast cells?
Basophils circulate in the blood, while mast cells are found mainly in tissues. Both participate in immune responses, particularly those involving allergy and inflammation.
Does this test measure all my white blood cells?
No. This is a specific part of a cell count or differential. The total white blood cell count and the results for the other white blood cell types provide additional context.
What does an abnormal basophil or mast cell result mean?
It may reflect an allergic or inflammatory condition, infection, medication effect, or another change in the blood. Your clinician should interpret the result alongside your symptoms and the other laboratory findings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy