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Basophilsnfrbld

Published: August 9, 2026Updated: August 15, 2026

This test measures the percentage of basophils, a type of white blood cell, in your blood to help evaluate your immune system and detect certain medical conditions.

Quick summary

{"Basophils are the least common type of white blood cell, making up less than 1% of all white blood cells","This test helps diagnose allergic reactions, infections, and certain blood disorders","Abnormal basophil levels may indicate underlying health conditions that need further evaluation","The test is performed on a blood sample and is usually part of a complete blood count (CBC)","Results are interpreted alongside other white blood cell types for accurate diagnosis"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
30180-4
Short code
BASO/WBC
Synonyms
Basophils NFr Bld
Category
chemistry
Sample
whole-blood
Container
EDTA (lavender/purple-top) vacuum blood collection tube
Units
N/A
Ref low
0.5
Ref high
1
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Automated hematology analyzer using flow cytometry and impedance (e.g., Sysmex XN series, Beckman Coulter DxH, Abbott CELL-DYN)
CPT
85025
SNOMED
7051007
Specimen volume
3-5 mL of whole blood (1 mL minimum for pediatric samples)
Stability
Stable for 4 hours at room temperature (20-25°C) or 24 hours refrigerated (2-8°C). Basophil counts should be performed within 2 hours of collection for optimal accuracy
Hemolysis max
100
Lipemia max
500
Icterus max
50
TAT
1–4 hours
Order
routine

What is this test?

The basophils test measures the percentage of basophils in your blood. Basophils are a type of white blood cell (leukocyte) that play an important role in your immune system. They are the least abundant type of white blood cell, typically making up less than 1% of all white blood cells in a healthy person.

Why is this test performed?

This test is usually performed as part of a complete blood count (CBC) with differential. Your healthcare provider may order this test to: evaluate your overall immune system health, investigate symptoms like unexplained allergic reactions, detect infections or inflammatory conditions, monitor certain blood disorders such as leukemia, or assess your response to certain treatments.

How is the test done?

A healthcare professional will draw a small sample of blood from a vein in your arm. The sample is then sent to a laboratory where it is analyzed using automated blood analyzers to determine the percentage and absolute count of basophils. The procedure is quick and generally takes only a few minutes.

What do the results mean?

Normal basophil levels typically range from 0 to 1% of total white blood cells, or approximately 0 to 0.1 x 10^9/L. Elevated basophil levels (basophilia) may indicate allergic reactions, chronic inflammation, infections (such as chickenpox or tuberculosis), certain leukemias, or autoimmune diseases. Low basophil levels (basopenia) are less common and may occur with hyperthyroidism, acute infections, prolonged stress, or as a side effect of certain medications.

Are there any risks?

The risks associated with this test are minimal and similar to any routine blood draw. You may experience slight bruising, bleeding, or dizziness at the puncture site. These symptoms usually resolve quickly. Serious complications are rare.

Reference range

Basophils: 0.5-1.0% of total leukocytes (absolute count: 0.02-0.10 x 10^3/µL). Leukocytes (WBC): 4.0-11.0 x 10^3/µLN/A

Specimen: whole-blood

No special preparation required. Specimen should be collected prior to administration of medications that may affect white blood cell counts when possible

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
No fasting is typically required for a basophil test. However, follow any specific instructions provided by your healthcare provider. It is advisable to inform your doctor about any medications or supplements you are taking, as some drugs can affect basophil levels.
Can stress affect my basophil count?
Yes, acute stress can sometimes cause a temporary decrease in basophil count (basopenia). Chronic stress may also affect immune cell counts. If you are experiencing high stress levels, discuss this with your healthcare provider when interpreting your results.
What happens if my basophil count is abnormal?
An abnormal basophil count alone does not provide a definitive diagnosis. Your healthcare provider will consider your symptoms, medical history, and results from other tests to determine the cause. Additional testing may be needed to identify the underlying condition.
Can allergies affect my basophil levels?
Yes, allergic reactions can cause elevated basophil levels (basophilia). This is because basophils play a key role in allergic responses by releasing histamine. If you have seasonal allergies or allergic conditions, your basophil count may be at the higher end of the normal range.
How often should this test be done?
The frequency of this test depends on your individual health situation. If you are being monitored for a specific condition like leukemia or allergies, your doctor may order this test regularly. For routine health checkups, it is typically included in the CBC which is performed annually or as recommended by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy