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Basophilsnfrbldmanual

Published: August 9, 2026Updated: August 16, 2026

A basophil count test measures the number of basophils, a type of white blood cell, in your blood to help evaluate your immune system and detect certain medical conditions.

Quick summary

{"Basophils are white blood cells that play a key role in allergic reactions and inflammation","The test uses a manual microscopic examination of a blood sample","Results can help diagnose allergies, infections, and blood disorders","Both percentage and absolute basophil counts may be reported","Abnormal results require follow-up with your healthcare provider"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
707-0
Short code
BASOMAN
Synonyms
Basophils NFr Bld Manual
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA K2/K3) vacuum collection tube; minimum 3 mL whole blood
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
manual-count
CPT
85007
SNOMED
30369004
Specimen volume
1-3 mL whole blood in EDTA tube (minimum 0.5 mL for pediatric samples)
Stability
Stable for 2 hours at room temperature (20-25°C) for manual differential; up to 24 hours refrigerated (2-8°C) if smear preparation is delayed; do not freeze
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
2–8 hours
Order
routine

What is this test?

The basophil count test measures the number of basophils in your blood. Basophils are the least common type of white blood cell, making up less than 1% of all white blood cells. Despite their small numbers, they play an important role in your immune system by releasing histamine during allergic reactions and helping to fight off parasites.

Why is this test performed?

Your doctor may order a basophil count as part of a complete blood count (CBC) with differential, or separately, to: evaluate allergic conditions, investigate unexplained symptoms like itching or hives, check for parasitic infections, monitor certain blood disorders such as leukemia, or assess inflammatory conditions.

How is the test performed?

A healthcare professional will draw a small sample of blood from a vein in your arm. The sample is then sent to a laboratory where a technician examines it under a microscope (manual differential count) to identify and count the different types of white blood cells, including basophils. Results are typically reported as either a percentage of total white blood cells or as an absolute count (number of basophils per microliter of blood).

How to prepare for the test

No special preparation is usually required for a basophil count. You can eat and drink normally before the test. However, always follow any specific instructions provided by your healthcare provider. Certain medications, such as corticosteroids, antihistamines, or chemotherapy drugs, may affect your basophil count, so inform your doctor about all medications you are taking.

Reference range

Adults: 0.5-1.0% of total leukocytes (relative) or 0-0.2 x 10^3/uL (absolute count). Slight variations exist based on laboratory-specific reference intervals.N/A

Specimen: whole-blood

No special patient preparation required. Fasting is not necessary. Avoid strenuous exercise immediately prior to specimen collection as it may transiently alter leukocyte distribution.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

What is the normal range for basophils?
Normal basophil count typically ranges from 0 to 1% of total white blood cells, or about 0 to 100 basophils per microliter of blood. However, normal ranges may vary slightly between laboratories.
Does a high basophil count mean I have cancer?
Not necessarily. While elevated basophils can sometimes be associated with certain blood cancers like leukemia, there are many more common causes such as allergies, infections, or inflammation. Your doctor will consider your complete medical history and other test results before making any diagnosis.
Can stress affect my basophil count?
Yes, acute stress can sometimes cause a temporary increase in basophils. Chronic stress or prolonged emotional difficulties may also influence white blood cell counts. However, significant or persistent changes should be discussed with your healthcare provider.
Do I need to do anything after the test?
After a blood draw, you may resume normal activities immediately. If you feel dizzy or lightheaded, rest for a few minutes before leaving. The small bandage can be removed after an hour or as instructed.
How often should basophil counts be checked?
The frequency of testing depends on your individual health situation. If you have a known condition requiring monitoring, your doctor will determine how often the test should be repeated. For routine check-ups, basophils are often included as part of a regular CBC.
  1. 1
    Basophils: What They Are, Function & Normal LevelsSource
  2. 2
    Complete Blood Count (CBC) with DifferentialSource
  3. 3
    Basophilia and BasopeniaSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy