Skip to content

Complete Blood Count (CBC)

Published: August 9, 2026Updated: August 16, 2026

This test measures basophils, a type of white blood cell, in a sample from your airways to help diagnose respiratory conditions.

Quick summary

{"Basophils are white blood cells that play a role in allergic reactions and immune responses","This test helps doctors diagnose asthma, allergies, and airway infections","The sample is collected from your airways through sputum or bronchial washing","High basophil levels may indicate inflammation, allergy, or chronic respiratory conditions","Results help guide treatment decisions for respiratory diseases"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30373-5
Short code
BASOBR
Synonyms
Basophils NFr Bronch
Category
chemistry
Sample
serum
Container
Sterile cytology container or saline-filled sterile collection container for bronchial washings; sterile glass slides with appropriate fixative for brushings/biopsy touch preparations
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Microscopic examination with manual differential cell count using Wright-Giemsa or similar stain on cytocentrifuged bronchial specimen
CPT
88104
SNOMED
272255000
Specimen volume
Minimum 1-2 mL of bronchial washing/aspirate or adequate cellular material on prepared slides; larger volumes (5-10 mL) preferred for optimal cytologic evaluation
Stability
Specimen should be delivered to laboratory within 1 hour of collection if held at room temperature; refrigerated (2-8°C) stability up to 24 hours; fixed slides stable indefinitely
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

A complete blood count (CBC) is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets, along with hemoglobin and hematocrit levels, to give your doctor a broad picture of your overall health.

The Basophils in Bronchial Specimen test measures the number and percentage of basophils in a sample collected from your airways. Basophils are a type of white blood cell (leukocyte) that play an important role in your immune system, particularly in responding to allergens and fighting certain infections.

This test is performed to screen for a wide range of conditions, such as anemia, infections, and blood disorders, to evaluate symptoms like fatigue or fever, and to monitor an existing condition or the effects of treatments such as chemotherapy on your blood cells.

This test is performed to help diagnose and monitor respiratory conditions such as asthma, allergic bronchitis, chronic obstructive pulmonary disease (COPD), and respiratory infections. By examining basophil levels in the bronchial specimen, doctors can understand the nature and severity of airway inflammation.

A sample is collected by drawing blood from a vein, usually in your arm. A healthcare professional will clean the site, wrap an elastic band around your upper arm, insert a small needle, and collect the blood into a tube. The procedure usually takes only a few minutes.

The sample is typically collected through one of two methods: (1) Sputum collection, where you cough up mucus from your airways into a container, or (2) Bronchial washing/brushing, where a thin tube (bronchoscope) is passed through your nose or mouth into your airways to collect cells and fluid. The method used depends on your specific medical condition and your healthcare provider's assessment.

Your results are compared with normal reference ranges. Abnormal levels may suggest conditions such as anemia, infection, inflammation, or clotting problems, but many factors can affect the numbers, so your doctor will interpret them together with your symptoms, medical history, and other test results.

Results are reported as either a count (number of basophils) or a percentage of total white blood cells. Elevated basophil levels may indicate allergic inflammation, asthma, or certain infections. Normal or low levels may suggest that respiratory symptoms are due to other causes. Your doctor will interpret your results in conjunction with your symptoms, medical history, and other test results.

The risks of a CBC are very low. You may feel a brief sting when the needle is inserted, and slight bruising or soreness at the puncture site can occur afterward. Serious complications, such as excessive bleeding or infection at the site, are extremely rare.

Sputum collection is generally safe with minimal risks. Bronchial procedures may carry slight risks including minor bleeding, sore throat, or temporary breathing discomfort. These procedures are performed by trained healthcare professionals who will ensure your safety throughout the collection process.

Reference range

Basophils/Leukocytes ratio in bronchial specimen: Basophils are typically rare (<1% of leukocytes); reported as percentage of total leukocytes or absolute count when clinically indicatedN/A

Specimen: serum

No special patient preparation required for specimen collection; however, if bronchoscopy is performed, patient should follow pre-procedure fasting instructions as directed by the performing physician

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated basophil levels in bronchial specimens are commonly associated with allergic asthma, allergic bronchitis, and eosinophilic bronchitis. Basophils release histamine and other inflammatory mediators that contribute to airway inflammation and symptoms like wheezing and shortness of breath. This test helps differentiate between allergic (eosinophilic) and non-allergic types of respiratory conditions, which guides treatment decisions including the use of antihistamines, corticosteroids, or allergen avoidance strategies.

In some cases, abnormal basophil levels may indicate parasitic infections or certain hematological conditions. The test is also valuable for monitoring disease progression and evaluating response to treatment in patients with chronic respiratory diseases.

Frequently asked questions

Do I need to prepare for this test?
Your healthcare provider will give you specific instructions. You may be asked to avoid eating or drinking for a certain period before sputum collection. If undergoing bronchoscopy, you may need to fast and temporarily stop certain medications. Always inform your doctor about any medications you are taking.
How long does it take to get results?
Results typically take 1-3 days, depending on the laboratory. Your healthcare provider will contact you with results or discuss them at your follow-up appointment.
What happens if my basophil levels are high?
High basophil levels in a bronchial specimen usually indicate allergic inflammation or asthma. Your doctor will consider your symptoms and may recommend additional tests or treatments such as allergy testing, inhaled corticosteroids, or other anti-inflammatory medications.
Is this test painful?
Sputum collection is not painful—just a cough. Bronchial procedures may cause mild discomfort; you will receive local anesthesia or sedation to minimize any discomfort during the procedure.
Can this test diagnose asthma?
This test alone cannot diagnose asthma, but it provides important information about the type of airway inflammation present. Asthma diagnosis is based on a combination of symptoms, medical history, physical examination, lung function tests, and this laboratory test.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy