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Basophilsnfrbronchmanual

Published: August 9, 2026Updated: August 16, 2026

This test counts basophils, a type of white blood cell, in a sample taken from the airways to help diagnose respiratory conditions.

Quick summary

{"Basophils are white blood cells that play a role in allergic reactions and inflammation","The test uses a manual microscope count of cells in a bronchial sample","Results help doctors diagnose infections, allergies, or other lung conditions","Sample is collected through bronchoscopy or sputum collection","Abnormal results may indicate asthma, allergies, or infection"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14625-8
Short code
BASOLBRN
Synonyms
Basophils NFr Bronch Manual
Category
chemistry
Sample
serum
Container
Sterile, leak-proof specimen container; bronchial washings collected in saline, brushings in appropriate transport medium. Label with patient identification, collection time, and specimen source.
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
86021
SNOMED
442930000
Specimen volume
Minimum 1-2 mL of bronchial washing/aspirate; brushings should be placed in appropriate cytology fixative or saline
Stability
Specimen should be processed within 1-2 hours of collection for optimal cell morphology. If delayed, refrigerate at 2-8°C; do not freeze. Stability is limited due to cell degradation.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The Basophil Count in Bronchial Specimen test measures the number of basophils in a sample collected from the airways (bronchi). Basophils are a type of white blood cell (leukocyte) that are part of your immune system. They help protect your body against infections and play a key role in allergic reactions and inflammation.

How is the sample collected?

The bronchial specimen is usually collected through one of two methods: (1) Bronchoscopy – a thin tube with a camera is passed through the nose or mouth into the airways to collect fluid or tissue samples, or (2) Sputum collection – you may be asked to cough up mucus from your airways into a container. The sample is then examined under a microscope by a laboratory technologist who manually counts the basophils.

Why might I need this test?

Your doctor may order this test if you have symptoms of a respiratory condition such as persistent cough, wheezing, shortness of breath, or chronic bronchitis. It helps determine if your symptoms are due to an allergic reaction, infection, asthma, or other inflammatory lung disease.

What do the results mean?

Results are typically reported as a percentage or absolute count of basophils in the sample. Higher than normal basophil counts may indicate allergic conditions, asthma, chronic inflammation, or certain infections. Lower than normal counts are less common but may occur in some autoimmune conditions or during severe infections. Your doctor will interpret your results based on your symptoms and other test findings.

Reference range

Reference ranges vary based on clinical context; basophils are typically reported as a percentage of total leukocytes identified in bronchial washings/brushings. Normal bronchial specimens generally show very low basophil counts (0-1%). Basophil elevation may suggest allergic or inflammatory airway disease.N/A

Specimen: serum

Patient preparation depends on specimen collection method (bronchoscopy with BAL, bronchial brushings, or washings). Follow institutional protocols for bronchoscopy preparation, including fasting prior to the procedure if sedation is required. No special preparation needed for specimen analysis itself.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Is the test painful?
If collected by bronchoscopy, you may experience some discomfort and a sore throat afterward. The procedure is usually done with sedation to minimize discomfort. Sputum collection is non-invasive and simply requires coughing into a container.
How long does it take to get results?
Results are typically available within 1-3 days, as the sample requires manual microscopic examination by a trained technologist.
Do I need to prepare for the test?
If undergoing bronchoscopy, you may need to fast for several hours before the procedure. Your doctor will provide specific instructions. For sputum collection, avoid eating or drinking immediately before collecting the sample to prevent contamination.
Can medications affect the results?
Yes, certain medications particularly corticosteroids and antihistamines can affect basophil counts. Inform your doctor about all medications you are taking before the test.
  1. 1
    MedlinePlus - BronchoscopySource
  2. 2
    American Lung Association - BronchoscopySource
  3. 3
    Mayo Clinic - BronchitisSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy