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Complete Blood Count (CBC)

Published: August 9, 2026Updated: August 16, 2026

A manual count test that measures basophils and other white blood cells in body fluid samples to help diagnose infections, inflammation, or other medical conditions.

Quick summary

{"This test counts basophils (a type of white blood cell) in body fluid","Helps detect infections, inflammatory conditions, or abnormal cell growth","The test is performed manually under a microscope by trained lab staff","Results help doctors determine the cause of fluid accumulation in the body","Different body fluids (pleural, peritoneal, synovial) can be tested"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12179-8
Short code
BASOFLM
Synonyms
Basophils NFr Fld Manual
Category
chemistry
Sample
serum
Container
Sterile, leak-proof collection tube or container (e.g., EDTA tube for cell count, heparin tube for some fluid types); plain sterile container acceptable for some fluid analyses
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
89051
SNOMED
44295002
Specimen volume
1-5 mL of body fluid depending on fluid type and clinical indication; minimum 0.5 mL recommended for manual count
Stability
Specimen should be analyzed as soon as possible, preferably within 1 hour of collection. If delay is expected, refrigerate at 2-8°C and process within 4 hours. Prolonged delay may result in cell lysis and inaccurate counts.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
1–4 hours
Order
routine

The complete blood count, or CBC, is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets. These cells carry oxygen throughout your body, fight infection, and help your blood clot properly when you are injured.

The Basophils/Leukocytes in Body Fluid test is a laboratory test that manually counts the number of basophils and other white blood cells (leukocytes) in a sample of body fluid. Basophils are a type of white blood cell that play a role in the body's immune response, particularly in allergic reactions and inflammation. This manual counting method involves examining the fluid sample under a microscope to identify and count these cells.

Your doctor may order a CBC as part of a routine checkup or to help find the cause of symptoms such as fatigue, weakness, fever, unexplained bruising, or bleeding. It is also used to monitor an existing health condition or to check how well a treatment is working over time.

This test is performed when there is an abnormal accumulation of fluid in a body cavity, such as pleural fluid (around the lungs), peritoneal fluid (in the abdomen), or synovial fluid (in joints). The test helps doctors determine the cause of the fluid buildup, which could be due to infection, inflammation, cancer, or other medical conditions. By counting basophils and other white blood cells, doctors can better understand what is causing the fluid accumulation.

A healthcare professional will draw a small sample of blood, usually from a vein in your arm, using a thin needle. The procedure takes only a few minutes, and you may feel a brief pinch when the needle goes in. The sample is then sent to a laboratory, where a machine analyzes your blood cells.

A sample of body fluid is collected by a healthcare provider through a procedure such as thoracentesis (for pleural fluid), paracentesis (for peritoneal fluid), or arthrocentesis (for joint fluid). The fluid sample is then sent to a laboratory where a trained technician examines it under a microscope. The technician manually counts the number of basophils and other white blood cells present in the sample. Results are typically reported as the number of cells per microliter (μL) or as a percentage of total white blood cells.

Your results will show whether your blood cell counts fall within the normal range. Values that are too high or too low may point to conditions such as anemia, infection, inflammation, or clotting problems. Your doctor will review your numbers with you, explain what they mean, and discuss whether any follow-up testing or treatment is needed.

Normal basophil counts in body fluid are typically very low or absent. An elevated basophil count may indicate an allergic reaction, parasitic infection, or certain types of leukemia. Elevated total white blood cell counts generally suggest infection or inflammation. Your doctor will interpret the results based on your specific symptoms, medical history, and other test results.

Reference range

Reference ranges vary by body fluid type. Normally basophils are rarely present in body fluids; leukocyte count depends on fluid source (e.g., synovial, pleural, peritoneal, CSF). Generally, basophils 0% of total leukocytes in most body fluids.N/A

Specimen: serum

No special patient preparation is generally required. Specimen collection is typically performed by a qualified healthcare professional via aspiration of the affected body fluid (e.g., thoracentesis, paracentesis, arthrocentesis, lumbar puncture) using aseptic technique.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps diagnose and monitor conditions affecting body cavities and joints. Elevated basophil counts may indicate allergic reactions, parasitic infections, or hematologic disorders. The test is particularly useful in distinguishing between transudate (caused by systemic conditions like heart failure or liver disease) and exudate (caused by local inflammation, infection, or malignancy). It also helps guide treatment decisions and monitor response to therapy.

Frequently asked questions

Is the test painful?
The fluid collection procedure may cause some discomfort or pain, similar to a blood draw. Local anesthesia is often used to minimize pain. The actual laboratory test (cell counting) does not cause any pain as it is performed on the collected sample.
How long does it take to get results?
Results are typically available within 1-2 days, but may take longer depending on the laboratory's processing time and the complexity of the analysis.
Are there any risks associated with this test?
The main risks are related to the fluid collection procedure, which may include bleeding, infection, or damage to surrounding tissues. These risks are generally low and the procedure is performed by experienced healthcare professionals.
Do I need to prepare for the test?
No special preparation is typically needed. Your healthcare provider will give you specific instructions if needed. Inform your doctor about any medications you are taking, as some may affect the test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy