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Basophilsnfrsnv

Published: August 9, 2026Updated: August 16, 2026

This test measures basophils and white blood cells in the fluid around your joints to help diagnose joint conditions.

Quick summary

{"A small sample of joint fluid is collected using a needle (arthrocentesis)","Elevated white blood cells often indicate inflammation, infection, or arthritis","Basophil count helps identify allergic or inflammatory joint conditions","Results guide treatment decisions for joint diseases","The procedure is generally safe but carries minor risks like infection or bleeding"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17833-5
Short code
SYNBASO
Synonyms
Basophils NFr Snv
Category
chemistry
Sample
fluid
Container
Sterile plain tube (red-top) or heparinized tube for synovial fluid collection; lavender-top (EDTA) tube acceptable for cell counts
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Manual microscopic differential cell count with Wright-Giemsa or May-Grünwald-Giemsa stained smear examined under light microscopy
CPT
89051
SNOMED
417270009
Specimen volume
1-2 mL of synovial fluid minimum; 3-5 mL preferred for complete cell count and differential
Stability
Room temperature: 1 hour; Refrigerated (2-8°C): up to 24 hours; Cell morphology best preserved if analyzed within 1 hour of collection
Hemolysis max
300
TAT
1–4 hours
Order
routine

What is this test?

The Basophils/Leukocytes in Synovial Fluid test analyzes the fluid that lubricates your joints. Synovial fluid is a viscous liquid that helps joints move smoothly. This test counts two important components: leukocytes (white blood cells), which fight infection and inflammation, and basophils, a type of white blood cell involved in allergic reactions and inflammatory responses.

During the test, a doctor inserts a thin needle into your joint (usually the knee) to withdraw a small amount of synovial fluid. The fluid is then sent to a laboratory where specialists count the number of white blood cells and basophils under a microscope or using automated equipment.

Reference range

Normally absent or very rare (≤1% of leukocytes) in healthy synovial fluid. Basophils are typically not reported in routine synovial fluid analysis unless specifically identified.N/A

Specimen: fluid

No special patient preparation required prior to arthrocentesis. Inform the ordering physician of any anticoagulant therapy as it may affect specimen collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings3

Frequently asked questions

Why do I need this test?
Your doctor may order this test if you have joint pain, swelling, stiffness, or limited movement. It helps determine whether your joint problem is caused by infection, inflammation, or other conditions, which is essential for choosing the right treatment.
Is the joint fluid collection painful?
You may feel some discomfort or pressure when the needle enters the joint, but the area is usually numbed with a local anesthetic. The procedure takes only a few minutes, and any discomfort typically resolves quickly.
How should I prepare for the test?
No special preparation is usually needed. Inform your doctor about any medications you're taking, especially blood thinners, as they may increase bleeding risk. Wear comfortable, loose-fitting clothing that allows easy access to the joint being tested.
When will I get my results?
Results are typically available within 1-3 days, depending on the laboratory. Your doctor will discuss the findings with you and explain what they mean for your specific condition.
Are there any risks from the joint fluid procedure?
Risks are minimal but may include temporary pain, swelling, bruising, or very rarely, infection or bleeding at the puncture site. These complications are uncommon and usually resolve on their own.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy