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Laboratory Test Overview: What It Is, How It Is Done, and Why Your Doctor Ordered It

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of basophils in fluid around the heart.

Quick summary

{"Detects basophils in pericardial fluid using microscopy","Helps diagnose causes of fluid accumulation around the heart","Basophils may indicate allergic or inflammatory conditions","Sample is collected via pericardiocentesis procedure","Results are reported as present or absent"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44042-0
Short code
BASOPF
Synonyms
Basophils Pcar Ql Micro
Category
chemistry
Sample
serum
Container
Sterile, leak-proof container; heparinized tube preferred to prevent clotting; EDTA tube acceptable for cell preservation
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light
CPT
89051
SNOMED
167992005
Specimen volume
Minimum 2 mL of pericardial fluid; preferably 5-10 mL for comprehensive cell differential analysis
Stability
Specimen should be delivered to the laboratory immediately after collection. If immediate processing is not possible, refrigerate at 2-8°C and analyze within 1 hour for optimal cell preservation and morphology.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
1–4 hours
Order
routine

This is a laboratory test that analyzes a small sample from your body to help your healthcare provider check how well your organs are working, look for early signs of illness, and make informed decisions about your ongoing care and treatment options.

The Basophils in Pericardial Fluid test is a laboratory analysis that examines fluid collected from the pericardium (the sac surrounding your heart) to detect the presence of basophils. Basophils are a type of white blood cell that play a role in your immune system and allergic responses. The test uses light microscopy to identify these cells in the fluid sample.

Most samples are collected at a clinic, hospital, or laboratory by a trained technician, often by drawing blood from a vein in your arm with a small needle, and the entire collection process usually takes only a few minutes to complete.

A doctor will collect pericardial fluid using a procedure called pericardiocentesis. During this procedure, a thin needle is inserted into the pericardial sac to withdraw fluid. The sample is then sent to a laboratory for analysis under a microscope to check for the presence of basophils and other cells.

Your provider may order this test as part of a routine checkup, to help diagnose the cause of symptoms you are experiencing, to monitor an existing health condition over time, or to find out how well a current treatment plan is working for you.

This test is usually ordered when a patient has pericardial effusion (accumulation of fluid in the pericardium). It helps doctors determine the cause of the fluid buildup, which could be due to infection, inflammation, cancer, or other conditions.

Reference range

Basophils are typically absent or rarely seen in normal pericardial fluid. Presence of basophils is reported as detected or not detected.N/A

Specimen: serum

No special patient preparation is required prior to pericardial fluid collection. Pericardiocentesis is performed by a qualified physician under sterile conditions, often guided by echocardiography.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The presence of basophils in pericardial fluid may indicate: allergic or hypersensitivity reactions, parasitic infections, certain inflammatory conditions, or in rare cases, hematologic disorders. When combined with other test results, this information helps doctors diagnose the underlying cause of pericardial effusion and guide appropriate treatment.

Frequently asked questions

Is this test painful?
The pericardiocentesis procedure may cause some discomfort. Local anesthesia is used to minimize pain during the procedure.
How long does it take to get results?
Results are typically available within a few days, as the sample requires microscopic examination by trained laboratory personnel.
What do positive results mean?
The presence of basophils suggests an allergic, inflammatory, or parasitic cause for the pericardial fluid. Your doctor will interpret this along with other test results to determine the cause.
Are there any risks from the procedure?
Risks include bleeding, infection, puncture of the heart, or pneumothorax (collapsed lung). These complications are rare, and the procedure is performed under careful monitoring.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy