Laboratory Test Overview: What It Is, How It Is Done, and Why Your Doctor Ordered It
This test checks for the presence of basophils in fluid around the heart.
{"Detects basophils in pericardial fluid using microscopy","Helps diagnose causes of fluid accumulation around the heart","Basophils may indicate allergic or inflammatory conditions","Sample is collected via pericardiocentesis procedure","Results are reported as present or absent"}
Key facts at a glance
- LOINC
- 44042-0
- Short code
- BASOPF
- Synonyms
- Basophils Pcar Ql Micro
- Category
- chemistry
- Sample
- serum
- Container
- Sterile, leak-proof container; heparinized tube preferred to prevent clotting; EDTA tube acceptable for cell preservation
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- microscopy-light
- CPT
- 89051
- SNOMED
- 167992005
- Specimen volume
- Minimum 2 mL of pericardial fluid; preferably 5-10 mL for comprehensive cell differential analysis
- Stability
- Specimen should be delivered to the laboratory immediately after collection. If immediate processing is not possible, refrigerate at 2-8°C and analyze within 1 hour for optimal cell preservation and morphology.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 1–4 hours
- Order
- routine
This is a laboratory test that analyzes a small sample from your body to help your healthcare provider check how well your organs are working, look for early signs of illness, and make informed decisions about your ongoing care and treatment options.
The Basophils in Pericardial Fluid test is a laboratory analysis that examines fluid collected from the pericardium (the sac surrounding your heart) to detect the presence of basophils. Basophils are a type of white blood cell that play a role in your immune system and allergic responses. The test uses light microscopy to identify these cells in the fluid sample.
Most samples are collected at a clinic, hospital, or laboratory by a trained technician, often by drawing blood from a vein in your arm with a small needle, and the entire collection process usually takes only a few minutes to complete.
A doctor will collect pericardial fluid using a procedure called pericardiocentesis. During this procedure, a thin needle is inserted into the pericardial sac to withdraw fluid. The sample is then sent to a laboratory for analysis under a microscope to check for the presence of basophils and other cells.
Your provider may order this test as part of a routine checkup, to help diagnose the cause of symptoms you are experiencing, to monitor an existing health condition over time, or to find out how well a current treatment plan is working for you.
This test is usually ordered when a patient has pericardial effusion (accumulation of fluid in the pericardium). It helps doctors determine the cause of the fluid buildup, which could be due to infection, inflammation, cancer, or other conditions.
Reference range
Basophils are typically absent or rarely seen in normal pericardial fluid. Presence of basophils is reported as detected or not detected.N/A
No special patient preparation is required prior to pericardial fluid collection. Pericardiocentesis is performed by a qualified physician under sterile conditions, often guided by echocardiography.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The presence of basophils in pericardial fluid may indicate: allergic or hypersensitivity reactions, parasitic infections, certain inflammatory conditions, or in rare cases, hematologic disorders. When combined with other test results, this information helps doctors diagnose the underlying cause of pericardial effusion and guide appropriate treatment.
Frequently asked questions
Is this test painful?
How long does it take to get results?
What do positive results mean?
Are there any risks from the procedure?
Sources
- 1
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy