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Bilirubin, Total

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Your liver’s ability to process bilirubin can signal potential liver health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61285-3
Short code
Bass IgE/IgE total %
Synonyms
Bass IgE/IgE total %
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Bilirubin is normally processed by your liver and excreted in bile. If your liver isn’t working well, bilirubin can build up in your blood, leading to jaundice (yellowing of skin/eyes). This test helps doctors check for liver problems, bile duct blockages, or red blood cell disorders.

What to Expect Before the Test

No special preparation is needed. You may have a blood draw from a vein in your arm. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Higher-than-normal levels may indicate liver disease, infections, or conditions like hemolysis (red blood cell breakdown). Lower levels are less common but could signal rare genetic disorders.

Common Causes of Abnormal Results

Elevated bilirubin can stem from liver disease (e.g., hepatitis), gallbladder issues, or hemolytic anemia. Low levels are rare but may relate to genetic factors or liver dysfunction.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Bilirubin

Frequently asked questions

How often will I need this test?
Your doctor may order this test periodically if you have liver-related symptoms, chronic conditions (like hemochromatosis), or during routine check-ups for certain groups (e.g., newborns for jaundice).
What if my results are out of range?
Your doctor will discuss your results with you. Elevated levels often prompt further testing (like liver function panels) to pinpoint the cause. Follow-up may include lifestyle changes, medications, or referrals to a specialist.
Can diet affect bilirubin levels?
Diet alone rarely changes bilirubin levels, but certain foods (e.g., high-fiber, cruciferous veggies) may indirectly support liver health. Avoid alcohol and excessive caffeine before testing if advised by your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy