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Bbigeminaabserqlif

Published: August 9, 2026Updated: August 15, 2026

This test detects antibodies against Babesia bigemina parasites in blood using immunofluorescence to diagnose babesiosis, a tick-borne disease.

Quick summary

{"Detects antibodies to Babesia bigemina, a parasite causing babesiosis","Uses immunofluorescence assay (IFA) for high sensitivity","Positive result indicates current or past infection","Spread by infected tick bites, similar to Lyme disease","Symptoms include fever, chills, sweats, and fatigue"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
22845-2
Short code
BABGMAB
Synonyms
B bigemina Ab Ser Ql IF
Category
chemistry
Sample
serum
Container
Serum separator tube (SST), red-top tube, or gold-top tube
Units
N/A
Ref low
80
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunofluorescence Assay (IFA)
CPT
86317
SNOMED
39517007
Specimen volume
1-2 mL serum (minimum 0.5 mL)
Stability
Serum stable for 7 days at 2-8°C; for extended storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles. Hemolyzed, lipemic, or icteric specimens may yield unreliable results.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

What is this test?

The Babesia bigemina Antibody test is a blood test that looks for antibodies (immune proteins) in your blood that your body makes in response to infection with Babesia bigemina, a microscopic parasite that infects red blood cells. The test uses a method called immunofluorescence assay (IFA), which is very good at detecting even small amounts of antibodies.

Why might I need this test?

Your doctor may order this test if you have symptoms of babesiosis, especially if you have been in areas where Babesia parasites are common. Symptoms typically appear 1-4 weeks after a tick bite and may include: fever, chills, sweats, headache, muscle aches, fatigue, nausea, and anemia (low red blood cell count). This test is also used to confirm a diagnosis when other tests are unclear.

What happens during the test?

A healthcare professional will draw a small sample of blood from a vein in your arm. The blood is sent to a lab where technicians will look for antibodies against Babesia bigemina using special fluorescent dyes that make the antibodies visible under a microscope. The test result is reported as 'positive' (antibodies found) or 'negative' (no antibodies found).

Reference range

Negative: No Babesia bigemina antibodies detected. Positive: Antibodies to Babesia bigemina detected at a titer of 1:80 or greater (or as defined by the performing laboratory). Titers of 1:80-1:320 suggest past exposure; titers ≥1:640 suggest recent or active infection. Results should be interpreted in conjunction with clinical findings and epidemiologic exposure history.N/A

Specimen: serum

No special patient preparation is required. Patients should inform their healthcare provider of any recent travel to endemic areas, history of tick bites, immunosuppressive conditions, or prior transfusion history, as these factors influence test interpretation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How is babesiosis treated?
Babesiosis is typically treated with prescription antiparasitic medications such as atovaquone plus azithromycin or clindamycin plus quinine. Treatment usually lasts 7-10 days. Your doctor will determine the best treatment plan for you.
Can I get babesiosis more than once?
Yes, it is possible to get babesiosis more than once. Even after successful treatment, antibodies may remain in your blood for months to years, but this does not provide complete immunity against future infections.
How can I prevent babesiosis?
Prevention includes: using insect repellent with DEET, performing tick checks after being outdoors, wearing long sleeves and pants in wooded areas, and promptly removing any attached ticks. If you find a tick attached to your skin, remove it carefully with tweezers and monitor for symptoms.
Is babesiosis contagious from person to person?
Babesiosis is not typically contagious from person to person. However, it can be transmitted through blood transfusions from an infected donor. Blood banks now screen for Babesia in some areas.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy