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Bburgdor41kdiggsnvqlib

Published: August 9, 2026Updated: August 16, 2026

这项检测用于在关节液中寻找伯氏疏螺旋体（导致莱姆病的细菌）的特定抗体，以帮助诊断莱姆病关节炎。

Quick summary

{检测关节液中针对伯氏疏螺旋体41kD蛋白的IgG抗体,帮助诊断莱姆病关节炎（莱姆病的晚期表现）,通常在关节液检测前，血液检查已提示莱姆病,采样过程需要在关节处抽取液体（关节穿刺术）,结果需要由医生结合临床症状综合判断}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30015-2
Short code
BB41IGGSF
Synonyms
B burgdor41kD IgG Snv Ql IB
Category
chemistry
Sample
fluid
Container
Sterile, leak-proof, screw-cap container; sterile cryovial preferred. Avoid containers with preservatives.
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoblot (Western Blot)
CPT
86617
SNOMED
416628003
Specimen volume
1-2 mL of synovial fluid
Stability
Room temperature: 2 hours; Refrigerated (2-8°C): 24 hours; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
300
TAT
24–72 hours
Order
routine

这是什么测试？

这是一项针对关节液中伯氏疏螺旋体（ Borrelia burgdorferi ）41kD蛋白特异性IgG抗体的免疫印迹检测。伯氏疏螺旋体是导致莱姆病的细菌。当莱姆病进展到关节炎阶段时，免疫系统会产生针对这种细菌的特定抗体。通过检测关节液中是否存在这些抗体，医生可以辅助诊断莱姆病关节炎。

免疫印迹（Immunoblot）是一种高度特异性的检测方法，可以检测针对特定蛋白质的抗体。41kD蛋白是伯氏疏螺旋体的一种重要抗原，针对它的IgG抗体通常在感染后一段时间内出现，提示为既往或持续感染。

Reference range

Negative: No IgG antibodies detected to the 41 kDa antigen band. Positive: IgG antibodies detected to the 41 kDa antigen band.N/A

Specimen: fluid

No special patient preparation is required. Specimen is collected via arthrocentesis (joint aspiration) performed by a qualified healthcare professional under sterile conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

这项检测主要用于莱姆病关节炎的诊断。莱姆病是由蜱虫叮咬传播的细菌感染，早期症状包括牛眼样皮疹、发热、头痛等。如果不及时治疗，细菌可能扩散到关节，引起莱姆病关节炎，表现为关节疼痛、肿胀，通常累及膝关节等大关节。

阳性结果提示关节液中存在针对伯氏疏螺旋体的IgG抗体，支持莱姆病关节炎的诊断。阴性结果不能完全排除莱姆病，需要结合其他检查和临床症状综合判断。

Frequently asked questions

为什么需要检测关节液而不是血液？
当莱姆病累及关节时，在关节液中检测到特异性抗体可以提供更直接的感染证据。关节液检测有助于确认关节炎是由莱姆病引起，而不是其他原因。
这个检测结果呈阳性意味着什么？
阳性结果表示在关节液中检测到了针对伯氏疏螺旋体41kD蛋白的IgG抗体，这支持莱姆病关节炎的诊断。但结果需要由医生结合您的症状、流行病学史（如是否在莱姆病流行区被蜱虫叮咬过）及其他检查结果综合判断。
检测结果阴性是否说明我没有莱姆病？
不一定。阴性结果可能表示没有莱姆病感染，但也可能是检测时间过早（抗体尚未产生）或免疫反应较弱的情况。医生会根据您的具体情况和其他检查结果做出判断。
关节液穿刺会痛吗？
在穿刺前，医生会使用局部麻醉药来麻醉穿刺区域，因此大部分患者只会感到轻微不适或压力感。穿刺后，少数患者可能出现短暂疼痛或肿胀。
  1. 1
    Mayo Clinic - Lyme diseaseSource
  2. 2
    CDC - Lyme Disease Diagnosis and TestingSource

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Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy