Bburgdorc6abseracnc
A blood test that checks for antibodies against Borrelia burgdorferi, the bacterium that causes Lyme disease.
{"Detects immune response to Lyme disease-causing bacteria","Used to diagnose Lyme disease infection","Blood sample required, taken from a vein in your arm","Results help determine if you have been exposed to Lyme disease","Results are typically available within a few days"}
Key facts at a glance
- LOINC
- 43075-1
- Short code
- LYC6
- Synonyms
- B burgdor C6 Ab Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top vacutainer tube
- Units
- N/A
- Ref low
- 5
- Ref high
- 9
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Enzyme Immunoassay (EIA) / Chemiluminescent Immunoassay (CLIA) for detection of antibodies against the C6 peptide of Borrelia burgdorferi
- CPT
- 86618
- SNOMED
- 416684001
- Specimen volume
- 1-2 mL of serum (minimum 0.5 mL)
- Stability
- Stable for 7 days at 2-8°C; stable for 30 days at -20°C or below for longer storage
- Hemolysis max
- 500
- Lipemia max
- 500
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
What is this test?
The Borrelia burgdorferi C6 Antibody test is a blood test that looks for specific antibodies in your blood that your immune system produces in response to the bacterium Borrelia burgdorferi, which causes Lyme disease. The C6 test is considered a highly specific test for Lyme disease detection.
Why is this test performed?
This test is primarily used to help diagnose Lyme disease, especially in patients who have symptoms suggestive of the infection. Symptoms may include a characteristic 'bull's-eye' rash (erythema migrans), fever, headache, fatigue, and joint or muscle pain. It is often ordered when a patient has been bitten by a tick or has been in areas where Lyme disease is common.
How is the test done?
A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood sample is then sent to a laboratory for analysis. The test measures the presence and level of C6 antibodies in your serum.
What do the results mean?
Results are typically reported as positive or negative. A positive result indicates that antibodies to Borrelia burgdorferi were detected, suggesting a current or past infection. A negative result means no antibodies were detected, which could mean you do not have Lyme disease or that the infection is very early (before antibodies have developed). Your healthcare provider will interpret the results in context with your symptoms and exposure history.
Are there any risks?
The risks associated with this blood test are minimal and include slight pain or bruising at the puncture site, lightheadedness, and in rare cases, infection. These risks are generally minor and resolve quickly.
Reference range
Negative: <5 U/mL; Equivocal: 5-9 U/mL; Positive: ≥10 U/mL (reference ranges may vary by laboratory and assay manufacturer)N/A
No fasting required. Patients should inform their healthcare provider of any recent antibiotic use, tick exposure, travel history, and vaccination status prior to testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Do I need to fast before this test?
How long does it take to get results?
Can this test detect early Lyme disease?
Will a positive result mean I have active Lyme disease?
Is the test painful?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy