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Complete Blood Count (CBC) Test: What It Measures, Why Your Doctor Orders It, and How to Understand Your Results

Published: August 9, 2026Updated: August 15, 2026

A blood test that detects IgA antibodies against Borrelia burgdorferi, the bacteria that causes Lyme disease.

Quick summary

{"The test checks for IgA antibodies to Lyme disease bacteria in your blood","It helps diagnose Lyme disease, especially in early stages","A positive result indicates exposure to Lyme disease bacteria","The test requires a simple blood draw","Results are typically available within a few days"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
110809-1
Short code
LYMEIGA
Synonyms
B burgdor IgA Msmt Ser
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube
Units
N/A
Ref low
0.8
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-linked immunosorbent assay (ELISA) or chemiluminescence immunoassay (CLIA) for detection of Borrelia burgdorferi IgA antibodies
CPT
86618
SNOMED
417620009
Specimen volume
1.0 mL serum (minimum 0.5 mL)
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

What is this test? A complete blood count, or CBC, is a routine blood test that measures the different cells circulating in your blood, including red blood cells, white blood cells, and platelets. Because these cells carry oxygen, fight infection, and help your blood clot properly, counting them gives your care team a broad picture of your overall health.

The Borrelia burgdorferi IgA Antibody test is a blood test that looks for IgA antibodies in your serum. IgA antibodies are one of the first types of antibodies your immune system produces when exposed to the Borrelia burgdorferi bacteria, which causes Lyme disease. This test helps healthcare providers determine if you have been infected with Lyme disease bacteria.

Why is this test performed? Doctors order a CBC for many reasons: as part of a routine checkup, to investigate symptoms such as fatigue, weakness, fever, bruising, or unusual bleeding, to help detect conditions like anemia, infection, or blood disorders, and to monitor how an ongoing condition or a treatment you are receiving is affecting your blood cells over time.

This test is primarily used to help diagnose Lyme disease. It may be ordered when a patient has symptoms suggestive of Lyme disease, such as the characteristic bull's-eye rash (erythema migrans), fever, headache, fatigue, or joint pain. It is particularly useful in the early stages of infection when IgA antibodies may be present before other antibody types. Your healthcare provider may also order this test if you have a history of potential tick exposure and are experiencing related symptoms.

How is the test done? A small sample of blood is drawn from a vein, usually on the inside of your elbow or the back of your hand. A healthcare professional cleans the site, wraps an elastic band around your upper arm, collects the blood into a tube using a thin needle, and then removes the band and needle. The procedure takes only a few minutes.

A healthcare professional will draw a small sample of blood from a vein in your arm. This blood sample will be sent to a laboratory where technicians will analyze it for the presence of IgA antibodies against Borrelia burgdorferi. The test does not require fasting, and you can resume your normal activities immediately after the blood draw. The sample is then processed using specialized laboratory techniques to detect the antibodies.

Understanding your results: Your report lists each blood cell type alongside a reference range showing the values considered normal for healthy adults. Values slightly outside the range are common and do not always mean illness, but results that are clearly high or low may point to conditions such as anemia, infection, inflammation, or clotting problems. Always review your results with your healthcare provider, who can interpret them together with your symptoms, medical history, and other test findings.

Test results are typically reported as positive or negative. A positive result means that IgA antibodies to Borrelia burgdorferi were detected in your blood, suggesting you have been exposed to the Lyme disease bacteria. A negative result means no IgA antibodies were detected. However, it is important to note that false negatives can occur, especially in very early infection before antibodies have developed, or if the infection is very recent. Your healthcare provider will interpret your results in context with your symptoms, medical history, and potentially other test results.

Reference range

Negative: <0.8 (antibody index); Equivocal: 0.8-1.0; Positive: >1.0. Results should be interpreted in conjunction with clinical findings and confirmatory Western blot testing as recommended by CDC two-tier testing algorithm.N/A

Specimen: serum

No fasting required. Patient should be informed that serological testing for Lyme disease is most reliable 2-4 weeks after onset of symptoms or tick exposure. Antibiotic treatment may affect antibody levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The Borrelia burgdorferi IgA Antibody test plays an important role in diagnosing Lyme disease. IgA antibodies typically appear earlier in Lyme disease infection than IgG antibodies, making this test particularly valuable for detecting early-stage disease. A positive IgA result supports the diagnosis of Lyme disease when combined with clinical symptoms and potential exposure history. However, this test is often used alongside other Lyme disease tests (such as IgG antibodies) for a more complete diagnostic picture. The test may also be used to monitor treatment response in some cases, as antibody levels may change after appropriate antibiotic therapy.

Frequently asked questions

Do I need to fast before this test?
No, you do not need to fast before this test. You can eat and drink normally before having your blood drawn.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the laboratory. Your healthcare provider's office will contact you with the results.
Can this test tell me how long I've had Lyme disease?
Not precisely. While IgA antibodies often appear early in infection, the test does not determine the exact duration of infection. Your healthcare provider will consider your symptoms and history to estimate how long you may have been infected.
If my result is negative, does that mean I don't have Lyme disease?
Not necessarily. A negative result could mean you do not have Lyme disease, or it could be a false negative. This can happen if the infection is very recent and antibodies have not yet developed, or if the test was performed too early. If you still have symptoms suggestive of Lyme disease, your healthcare provider may recommend repeat testing or additional tests.
What should I do if my test is positive?
If your test is positive, your healthcare provider will discuss treatment options with you. Lyme disease is typically treated with antibiotics, and early treatment is generally very effective. Follow your healthcare provider's instructions carefully and complete the full course of treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy