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Bburgdorigaserqlia

Published: August 9, 2026Updated: August 16, 2026

This blood test detects IgA antibodies against Borrelia burgdorferi, the bacterium that causes Lyme disease, to help diagnose if you have been infected.

Quick summary

{"Detects IgA antibodies produced in response to Lyme disease bacteria","Helps diagnose Lyme disease infection, often alongside IgG and IgM tests","A positive result suggests current or recent infection","Testing is typically done 2-4 weeks after potential tick exposure","Results should be interpreted with your symptoms and exposure history"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16478-0
Short code
LYMEIGA
Synonyms
B burgdor IgA Ser Ql IA
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme Immunoassay (EIA)
CPT
86618
SNOMED
387681000
Specimen volume
1 mL serum
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What is this test?

The Borrelia burgdorferi IgA Antibody test is a blood test that looks for IgA antibodies in your blood. IgA antibodies are proteins your immune system makes to fight against Borrelia burgdorferi, the bacteria transmitted through tick bites that causes Lyme disease. This test uses immunoassay technology to detect whether these specific antibodies are present in your serum sample.

Why is this test performed?

Your healthcare provider may order this test if you have symptoms of Lyme disease or if you know or suspect you have been bitten by a tick. Common symptoms of Lyme disease include a bull's-eye rash (erythema migrans), fever, headache, fatigue, and muscle aches. Early detection of Lyme disease is important because treatment with antibiotics is most effective when started early.

How is the test done?

A healthcare professional will draw a small blood sample from a vein in your arm. The blood is collected in a tube and sent to a laboratory for analysis. The laboratory uses special tests (immunoassays) to detect whether IgA antibodies against Borrelia burgdorferi are present in your blood. You do not need to fast or prepare in any special way for this test.

What do the results mean?

Results are typically reported as either 'Positive' (antibodies detected) or 'Negative' (no antibodies detected). A positive or reactive result suggests that your immune system has produced IgA antibodies in response to a current or recent Lyme disease infection. However, it can take 2-4 weeks after infection for antibodies to become detectable, so testing too early may give a false negative. A negative result does not completely rule out Lyme disease, especially if you have symptoms.

Reference range

NegativeN/A

Specimen: serum

No special preparation required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How soon after a tick bite should I get tested?
It is generally recommended to wait at least 2-4 weeks after a tick bite or symptom onset before getting tested. This allows your immune system enough time to produce detectable antibodies. Testing immediately after a tick bite may give a false negative result.
Do I need to do anything to prepare for this test?
No special preparation is needed. You can eat and drink normally before the test. Simply inform your healthcare provider about any medications or supplements you are taking.
Is a positive result always meaning I have Lyme disease?
Not necessarily. A positive IgA result indicates that your immune system has produced antibodies against Borrelia burgdorferi, but there is a small chance of false positives due to cross-reactivity with other infections or conditions. Your healthcare provider will interpret the result together with your symptoms, exposure history, and other test results.
What happens if my test is negative but I still have symptoms?
If your test is negative but you have symptoms of Lyme disease or known tick exposure, your healthcare provider may recommend repeat testing in a few weeks or may proceed with treatment based on your clinical presentation. Early Lyme disease may not yet show positive antibody results.
Can this test tell me if I'm cured after treatment?
No, this test is not used to monitor treatment response or determine if the infection is cured. Antibody tests may remain positive for months or even years after successful treatment, which is why they are used for diagnosis rather than monitoring treatment effectiveness.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy