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Understanding Your Laboratory Test: A Patient's Guide to What It Is, How It Is Done, and Why It Matters for Your Health

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic markers of antibiotic-resistant bacteria using molecular methods.

Quick summary

{"Identifies genes that make bacteria resistant to carbapenem antibiotics","Helps doctors choose the right antibiotics for treatment","Important for infection control in hospitals","Performed on a blood serum sample","Results guide treatment decisions for serious infections"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85502-3
Short code
CPRG
Synonyms
BCR gene pnl Islt/Spm
Category
chemistry
Sample
serum
Container
Sterile transport container for bacterial isolate or appropriate NAAT transport medium. For serum: red-top or serum separator tube (SST); for cultures: pure bacterial isolate on appropriate media submitted on a culture slant or swab in transport medium
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
CPT
87150 (Culture, typing); 87798 (Amplified probe technique, each organism, each probe); or 87500-87502 (Infectious agent detection by nucleic acid, other)
SNOMED
122450008 | Molecular genetics procedure| ; 425010008 | Carbapenemase resistance gene detection|
Specimen volume
1-2 mL serum; or pure bacterial isolate from culture; or appropriate swab/tissue specimen per source
Stability
Serum: Room temperature 24 hours; Refrigerated (2-8°C) up to 7 days; Frozen (-70°C or lower) for extended storage. Bacterial isolate: Room temperature up to 24 hours; refrigerated transport preferred. Nucleic acid extract: -20°C or -80°C for prolonged storage.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–72 hours
Order
routine

This test is a laboratory procedure that helps your healthcare provider learn important information about your health. By analyzing a sample in a medical laboratory, the test can detect signs of illness, confirm a suspected diagnosis, or track how a condition is changing over time. Your provider uses the results, together with your symptoms and medical history, to make informed decisions about your care.

The Carbapenemase Resistance Genes Panel is a molecular genetic test that detects specific genes in bacteria that cause resistance to carbapenem antibiotics. Carbapenems are powerful antibiotics used to treat serious bacterial infections. When bacteria carry these resistance genes, they can break down the antibiotic, making treatment ineffective.

The test is usually performed by a trained healthcare professional, such as a nurse or phlebotomist. In most cases, a small sample of blood is drawn from a vein in your arm using a sterile needle, although some tests use urine, saliva, or a swab from another part of the body. The collection typically takes only a few minutes, and the sample is then sent to a laboratory where specialized equipment and trained technicians analyze it. Once the analysis is complete, your results are shared with your provider, who will discuss them with you.

A blood sample is collected from you and sent to the laboratory. Scientists use molecular techniques to identify genetic material (DNA) from bacteria that may be present in your blood. The test looks for specific genes known to cause carbapenem resistance, such as KPC, NDM, VIM, IMP, and OXA-48-like genes.

This test is important because it gives your healthcare team objective information that cannot always be gathered from a physical exam alone. The results can help identify a medical condition early, when treatment is often most effective, guide the choice of medication or therapy, and show whether a current treatment plan is working. In some cases, the test is also used to screen for health problems before symptoms appear, which can lead to earlier care and better long-term outcomes.

This test is crucial for several reasons. First, it helps your doctor select the most effective antibiotic for your infection. Second, it helps prevent the spread of antibiotic-resistant bacteria in healthcare settings. Third, it provides important information for infection control measures in hospitals to protect other patients.

Reference range

Negative (No carbapenemase resistance genes detected). A negative result does not exclude the presence of other resistance mechanisms or genes not included in the panel.N/A

Specimen: serum

No special patient preparation required. Specimen should be collected prior to initiation of antimicrobial therapy whenever possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The detection of carbapenemase resistance genes has major clinical implications. It confirms carbapenem-resistant Enterobacteriaceae (CRE) infection, which are considered urgent threats by health authorities due to their limited treatment options. This information directly impacts antibiotic selection, infection control protocols, and patient isolation measures. Early detection helps prevent outbreaks in hospital settings and guides appropriate therapeutic strategies for life-threatening infections.

Frequently asked questions

Who needs this test?
This test is typically ordered for patients with suspected or confirmed infections who have not responded to standard antibiotic treatments. It is commonly used for patients with bloodstream infections, pneumonia, urinary tract infections, or intra-abdominal infections when carbapenem resistance is suspected.
How long does it take to get results?
Results are usually available within 24-48 hours, as this is a molecular test that does not require bacterial culture. This faster turnaround time compared to traditional culture methods allows for quicker treatment decisions.
Does a positive result mean I have an infection?
A positive result indicates the presence of bacteria with carbapenemase resistance genes. Your doctor will interpret this result along with your clinical symptoms and other test results to determine if you have an active infection that requires treatment.
What happens if the test is positive?
If positive, your healthcare team will implement additional infection control precautions to prevent spread. They will also select alternative antibiotics that are still effective against the resistant bacteria. You may be placed in isolation to protect other patients.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy