Complete Blood Count (CBC): What You Need to Know
This test detects antibodies against Babesia divergens parasite in blood using immunofluorescence, used to diagnose tick-borne babesiosis infection.
{"Detects antibodies to Babesia divergens parasite transmitted by ticks","Used to confirm diagnosis of babesiosis when symptoms suggest infection","Results indicate whether your immune system has responded to the parasite","Positive result suggests current or recent infection","Negative result may mean no infection or test performed too early"}
Key facts at a glance
- LOINC
- 22854-4
- Short code
- BABDV
- Synonyms
- B divergens Ab Ser Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top tube (no anticoagulant)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Immunofluorescence Assay (IFA)
- CPT
- 86256
- SNOMED
- 395140002
- Specimen volume
- 1.0 mL serum (minimum 0.5 mL)
- Stability
- Stable for 7 days at 2-8°C. For prolonged storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 50
- TAT
- 24–72 hours
- Order
- routine
The complete blood count, or CBC, is one of the most common blood tests. It measures the different cells that make up your blood, including red blood cells, white blood cells, and platelets, and gives your healthcare provider a broad picture of your overall health.
The Babesia divergens antibody test is a blood test that detects whether your immune system has produced antibodies against Babesia divergens, a parasite that causes babesiosis. This parasite is transmitted through the bite of infected ticks, primarily the Ixodes ricinus tick found in Europe. The test uses a method called immunofluorescence to identify these specific antibodies in your blood sample.
This test is performed during routine checkups to screen for health problems, to help diagnose conditions such as anemia, infections, and blood disorders, to investigate symptoms like fatigue or fever, and to monitor how well treatments are working over time.
Your healthcare provider may order this test if you have symptoms of babesiosis, especially if you have been exposed to tick-infested areas or have a history of tick bites. Symptoms of babesiosis typically include fever, chills, sweats, headache, muscle aches, fatigue, and sometimes hemolytic anemia. This test helps confirm whether your symptoms are caused by Babesia divergens infection rather than other similar illnesses like malaria or Lyme disease.
A healthcare professional will draw a small sample of blood, usually from a vein in your arm, using a thin needle. The procedure takes only a few minutes and causes little more than a brief pinch, and the sample is then sent to a laboratory for analysis.
A healthcare professional will draw a small blood sample from a vein in your arm. This sample is then sent to a laboratory where technicians will use immunofluorescence techniques to detect Babesia divergens-specific antibodies. The test looks for the presence (positive) or absence (negative) of these antibodies in your serum.
Your results show whether your red blood cell, white blood cell, and platelet counts fall within normal ranges. Values outside these ranges may suggest anemia, infection, inflammation, or clotting problems, but your doctor will interpret them together with your symptoms, medications, and medical history before making any diagnosis.
A positive result indicates that antibodies to Babesia divergens were detected in your blood, suggesting that you have been infected with this parasite. However, antibodies can persist for months or even years after recovery, so a positive result may indicate either a current active infection or a past infection. A negative result means no antibodies were detected, which could mean you are not infected, or the test was performed too early in the infection before antibodies developed. Your healthcare provider will interpret your results in context with your symptoms and exposure history.
Reference range
Negative: No Babesia divergens antibodies detected. Positive: Antibodies to Babesia divergens detected at a titer of ≥1:64 (or as defined by the performing laboratory). Titers between 1:16 and 1:64 may indicate past exposure or early infection and should be interpreted in clinical context.N/A
No special patient preparation is required. Fasting is not necessary. Patients should inform their healthcare provider of any recent travel to endemic areas, tick exposure, blood transfusion history, or immunosuppression, as these factors influence result interpretation.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Babesiosis is a tick-borne disease caused by Babesia parasites that infect red blood cells. Babesia divergens is the primary species causing human babesiosis in Europe. The disease can range from asymptomatic to severe, particularly in individuals without a spleen, elderly patients, or those with weakened immune systems. Severe cases may lead to hemolytic anemia, jaundice, renal failure, and even death if left untreated. This antibody test is an important tool for diagnosis, especially in endemic areas during tick season. Treatment typically involves antiprotozoal medications such as atovaquone plus azithromycin or clindamycin plus quinine.
Frequently asked questions
How is babesiosis transmitted besides tick bites?
When should I have this test done after a tick bite?
Do I need to fast before this test?
Can this test distinguish between current and past infection?
Is babesiosis the same as Lyme disease?
Sources
- 1CDC - BabesiosisSource
- 2Mayo Clinic - BabesiosisSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy