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Benzeneringiggseracnc

Published: August 9, 2026Updated: August 15, 2026

This blood test detects IgG antibodies that your immune system may produce in response to benzene or benzene-containing compounds.

Quick summary

{"Measures IgG antibodies against benzene ring structures in your blood","Used primarily in occupational health to assess chemical exposure","A simple blood draw is required; no special preparation is typically needed","Results help healthcare providers evaluate potential benzene exposure","Discuss any exposure history with your doctor for accurate interpretation"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
16441-8
Short code
BENZRNGG
Synonyms
Benzene ring IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacutainer tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-linked immunosorbent assay (ELISA) or fluorescence enzyme immunoassay (FEIA) for detection of IgG antibodies specific to benzene ring hapten conjugates
CPT
83516 (Immunoassay for analyte other than infectious agent antibody or infectious agent antigen; qualitative or semiquantitative, multiple-step method)
Specimen volume
1–2 mL of serum (minimum 0.5 mL)
Stability
Stable at room temperature for 8 hours; refrigerated at 2–8°C for 7 days; frozen at -20°C or below for up to 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
200
Icterus max
40
TAT
48–120 hours
Order
routine

What is this test?

The Benzene Ring IgG Antibody test is a blood test that measures the presence and level of IgG (immunoglobulin G) antibodies directed against benzene ring structures. Benzene is a chemical compound found in petroleum, tobacco smoke, and certain industrial settings. When the body detects benzene or substances containing benzene rings, the immune system may produce specific antibodies as part of the body's defense response.

How is the test performed?

A healthcare professional will draw a small blood sample from a vein in your arm. The sample is then sent to a laboratory where it is analyzed to detect and measure Benzene Ring IgG antibodies. The procedure is quick and similar to other routine blood tests.

Reference range

Reference values vary by laboratory; results are typically reported as negative, equivocal, or positive based on class-specific IgG antibody levels. Generally, values below 0.35 kU/L are considered negative, 0.35–0.70 kU/L equivocal, and >0.70 kU/L positive.N/A

Specimen: serum

No special patient preparation is required prior to specimen collection. However, patients should be advised that recent antihistamine or immunosuppressive therapy may affect antibody titers.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
Typically, no fasting is required for this test. However, always follow your healthcare provider's specific instructions.
How long does it take to get results?
Results are usually available within a few days to a week, depending on the laboratory.
What do positive results mean?
A positive result indicates that IgG antibodies against benzene ring structures were detected in your blood. This may suggest exposure to benzene or related compounds. Your healthcare provider will discuss what this means in the context of your specific situation.
Is this test routine?
This is not a routine test and is typically ordered by occupational health specialists or physicians when there is a specific concern about benzene exposure.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy