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Complete Blood Count (CBC) Test: What Patients Should Know

Published: August 9, 2026Updated: August 16, 2026

A urine test that detects the presence of benzodiazepines, a class of medications commonly prescribed for anxiety and sleep disorders.

Quick summary

{"This test checks if benzodiazepine medications are present in your urine","It is commonly used for drug screening, monitoring medication compliance, or evaluating suspected overdose","Results are typically reported as positive or negative based on a specific cutoff level","Certain prescription medications and supplements may cause false positive results","Discuss any medications you are taking with your healthcare provider before the test"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
19283-1
Short code
BENZO-UR
Synonyms
Benzodiaz CtO Ur Scn-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine collection container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
CPT
80307
SNOMED
395171001
Specimen volume
30 mL minimum
Stability
Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days; Room temperature: 48 hours
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

A complete blood count (CBC) is a routine blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets. Doctors order it to check your overall health and to help detect a wide range of conditions, such as infections, anemia, and other blood disorders. It is often part of a regular checkup and can provide important clues about how well your body is working.

The Benzodiazepine Urine Screen is a diagnostic test that detects the presence of benzodiazepines in your urine. Benzodiazepines are a class of prescription medications (such as Valium, Xanax, Ativan, and Klonopin) typically used to treat anxiety, insomnia, muscle spasms, and seizure disorders. This screening test uses a cutoff concentration to determine whether the level of benzodiazepines in your urine is above or below a threshold that would be considered positive.

The test is performed by drawing a small sample of blood, usually from a vein in your arm. A healthcare professional will clean the area, place a band around your upper arm, and use a needle to collect the blood into a tube. The sample is then sent to a laboratory where a machine counts and evaluates your blood cells. The procedure itself takes only a few minutes and causes little more than a brief pinch.

A urine sample is collected in a sterile container. The sample is then analyzed in a laboratory using immunoassay or mass spectrometry methods to detect benzodiazepines or their metabolites. The test result is reported as either positive (above the cutoff) or negative (below the cutoff). If positive, further confirmatory testing may be performed to identify the specific benzodiazepine present.

Preparation for a CBC is usually very simple. In most cases, no special preparation is needed, and you can eat and drink normally before the test. However, if your doctor ordered the CBC together with other blood tests, such as a fasting glucose test, you may be asked not to eat or drink anything except water for several hours beforehand. Tell your provider about any medicines or supplements you take, and wear loose clothing so the blood draw is easier.

No special preparation is typically required for this test. However, it is important to inform your healthcare provider about all prescription medications, over-the-counter drugs, and supplements you are taking, as some substances may interfere with test results. Certain medications, including some antidepressants and anticonvulsants, may cause false positive results.

Your results will show whether the levels of red blood cells, white blood cells, and platelets are within the normal range. Abnormal values may point to conditions such as anemia, infection, inflammation, or problems with blood clotting. Keep in mind that many factors, including dehydration, stress, or certain medications, can temporarily affect your counts. Your doctor will interpret the results together with your symptoms and medical history and may order additional tests if something needs a closer look.

A negative result means no benzodiazepines were detected in your urine above the test cutoff level. A positive result indicates that benzodiazepines or their metabolites were detected above the threshold. It is important to discuss your results with your healthcare provider, who will interpret them in the context of your medical history and current medications.

Reference range

Negative (below cutoff threshold of 200 ng/mL or 300 ng/mL depending on laboratory protocol)N/A

Specimen: urine

No special preparation required. Patient should be informed that certain prescription medications may cause positive results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The benzodiazepine urine screen is used for multiple clinical purposes: monitoring patients on benzodiazepine therapy for compliance, detecting unauthorized or illicit use, evaluating suspected intentional or accidental overdose, workplace or pre-employment drug screening, and monitoring for drug interactions in patients taking multiple medications. The test helps healthcare providers ensure patient safety and appropriate medication management.

Frequently asked questions

How long do benzodiazepines stay detectable in urine?
Benzodiazepines can typically be detected in urine for 1 to 6 days after use, depending on the specific medication, dosage, frequency of use, and individual metabolism. Long-acting benzodiazepines like diazepam may be detectable longer than short-acting ones like alprazolam.
Can natural supplements cause a positive result?
Certain herbal supplements and foods are not typically associated with false positive benzodiazepine results. However, some prescription medications, such as certain antidepressants (like sertraline), anticonvulsants (like carbamazepine), and pain medications may potentially cause false positive results. Always inform your healthcare provider about all medications you are taking.
Will a positive result show which specific benzodiazepine I took?
Initial screening tests typically only indicate whether benzodiazepines are present. If a confirmatory test is performed (such as gas chromatography-mass spectrometry), it can identify the specific benzodiazepine compound. Discuss with your healthcare provider if specific identification is needed.
Do I need to fast before this test?
No fasting is required for a urine benzodiazepine screen. You can eat and drink normally before providing the urine sample.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy