Understanding Your Laboratory Test: A Patient Guide to What the Test Is, How the Sample Is Collected, Why It Is Done, and What the Results Mean
This test detects benzodiazepine medications in stomach fluid to help diagnose poisoning or overdose.
{"Measures benzodiazepine levels in stomach fluid","Helps diagnose accidental or intentional overdose","Sample collected through stomach tube or aspiration","Results help doctors determine treatment","Different benzodiazepines may show different concentrations"}
Key facts at a glance
- LOINC
- 33560-4
- Short code
- BENZGAS
- Synonyms
- Benzodiaz Gast-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Sterile, leak-proof plastic container without preservative; gastight container with sodium fluoride may be used for preservation
- Units
- N/A
- Ref low
- 0
- Ref high
- 50
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Immunoassay with confirmation by Gas Chromatography-Mass Spectrometry (GC-MS) or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
- CPT
- 80307
- SNOMED
- 395171001
- Specimen volume
- 5-10 mL of gastric fluid
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–48 hours
- Order
- routine
This test is a laboratory analysis that measures specific substances in your body to help your doctor evaluate your overall health, screen for certain conditions, diagnose a possible illness, monitor an ongoing disease, or check how well a treatment is working over time.
The Benzodiazepine test in gastric fluid is a laboratory test that detects and measures the presence of benzodiazepine medications in the stomach contents. Benzodiazepines are a class of prescription drugs commonly used to treat anxiety, insomnia, seizures, and muscle spasms. Examples include diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), and clonazepam (Klonopin).
A trained healthcare professional will collect your sample using a standard procedure, which may involve drawing a small amount of blood from a vein in your arm, obtaining a urine specimen in a sterile container, or taking a swab from the affected area, and the process is usually quick and well tolerated.
The sample is collected from the stomach through a nasogastric (NG) tube or during gastric lavage (stomach pumping). This procedure is typically performed in an emergency department or hospital setting when a benzodiazepine overdose is suspected. The healthcare provider may also collect vomit or stomach contents if the patient has vomited.
Your doctor orders this test to gather objective information about what is happening inside your body, confirm or rule out a suspected condition, establish a baseline before starting a new medication, track changes in your health between visits, or adjust your treatment plan based on measurable findings.
This test is primarily ordered when a patient shows symptoms of drug poisoning or overdose, such as extreme drowsiness, confusion, slurred speech, difficulty breathing, or loss of consciousness. It helps healthcare providers determine if benzodiazepines are involved and guide appropriate treatment. The test may also be used in forensic cases or when monitoring patients for drug exposure.
Your results will show whether your values fall within the normal reference range for this test; results within range generally suggest no abnormality, while values that are higher or lower than expected may point to a condition that needs further evaluation, and your doctor will interpret them together with your symptoms, medical history, and other test findings before recommending next steps.
A positive result indicates that benzodiazepines are present in the stomach. The concentration may help estimate how much was ingested and how long ago. However, the amount in stomach fluid does not directly correlate with blood levels or toxicity. A negative result does not completely rule out benzodiazepine use, as the drugs may have already moved out of the stomach or been metabolized.
Reference range
Negative: <50 ng/mL (cutoff varies by laboratory and assay). Therapeutic monitoring ranges are not well established for gastric fluid specimens.N/A
No fasting required. Specimen is typically collected via gastric lavage or nasogastric tube in emergency or toxicology settings.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is crucial in emergency medicine for diagnosing benzodiazepine overdose, which can be life-threatening especially when combined with alcohol or other depressants. It helps guide treatment decisions including whether to use the reversal agent flumazenil, provide supportive care, or perform gastric decontamination. The test is also valuable in toxicology screening and forensic investigations where drug ingestion is suspected.
Frequently asked questions
Is this test painful?
How long does it take to get results?
Can this test detect all types of benzodiazepines?
Do I need to fast before this test?
What happens if the test is positive?
Sources
- 1
- 2
- 3LOINC Code ReferenceSource
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy