Benzodiazmsmtsal
A saliva test that measures benzodiazepine levels in your oral fluid to help monitor medication use or detect drug exposure.
{"This test uses a saliva sample to detect benzodiazepine medications","It helps doctors monitor if you are taking your medication as prescribed","The test is simple, non-invasive, and can be done at a clinic or at home","Results can show if benzodiazepines are present in your system","It may be used for medication management, compliance checking, or in certain screening situations"}
Key facts at a glance
- LOINC
- 110024-7
- Short code
- BENZSAL
- Synonyms
- Benzodiaz Msmt Sal
- Category
- chemistry
- Sample
- serum
- Container
- Saliva collection device (oral fluid collection tube with stabilizing buffer, e.g., Quantisal, Intercept, or equivalent)
- Units
- N/A
- Ref low
- 0
- Ref high
- 1
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–99 years
- Method
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or Enzyme-Linked Immunosorbent Assay (ELISA) for screening with confirmatory LC-MS/MS
- CPT
- 80307
- SNOMED
- 395170001
- Specimen volume
- 1-2 mL of oral fluid (minimum 0.5 mL)
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
What is this test?
The Benzodiazepine Saliva Test is a laboratory test that measures the amount of benzodiazepines in your saliva (also called oral fluid). Benzodiazepines are a class of prescription medications commonly used to treat anxiety, sleep disorders, muscle spasms, and seizures. Common benzodiazepines include lorazepam (Ativan), diazepam (Valium), alprazolam (Xanax), clonazepam (Klonopin), and midazolam (Versed).
How is the test done?
A healthcare provider will collect a sample of your saliva using a special swab or collection device. The swab is placed in your mouth, usually under your tongue or against your cheek, for a few minutes to absorb enough saliva. The sample is then sent to a laboratory for analysis. The test is quick, painless, and does not require blood drawing.
Why might I need this test?
Your doctor may order this test to: monitor if you are taking your benzodiazepine medication as prescribed, check for compliance with your treatment plan, evaluate if benzodiazepines may be causing certain symptoms, or in some cases, for screening purposes in workplace or forensic settings.
Reference range
Negative: < cutoff threshold (typically <1 ng/mL for most benzodiazepines). Cutoff values vary by specific benzodiazepine analyte and laboratory protocol.N/A
No special preparation required. Patients should avoid eating, drinking, or using oral hygiene products for at least 10 minutes prior to specimen collection to prevent sample contamination or dilution.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Do I need to prepare for the test?
How long does it take to get results?
What do the results mean?
Is the test accurate?
Will my insurance cover this test?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy