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Complete Blood Count (CBC)

Published: August 9, 2026Updated: August 16, 2026

A urine test that detects the presence of benzodiazepines, a class of commonly prescribed medications for anxiety and sleep disorders.

Quick summary

{"This test checks if benzodiazepine medications are present in your urine","Benzodiazepines include common drugs like diazepam, lorazepam, and alprazolam","A positive result means the medication or its breakdown products were detected","The test is commonly used for medication monitoring or substance abuse screening","Results should be discussed with your healthcare provider"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3387-8
Short code
BENZ-U
Synonyms
Benzodiaz Pos Ur
Category
chemistry
Sample
urine
Container
Sterile, leak-proof urine collection container without preservatives; for forensic/legal specimens, chain-of-custody container with tamper-evident seal is required
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay screening (e.g., EMIT, CEDIA, or KIMS) with confirmation by Gas Chromatography-Mass Spectrometry (GC-MS) or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT
80307
SNOMED
16712008
Specimen volume
30-50 mL of random urine; minimum 10 mL required for testing
Stability
Ambient temperature: 48 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. For forensic specimens, refrigerate immediately at 2-8°C.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–72 hours
Order
routine

A complete blood count (CBC) is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets. It gives your doctor important information about your overall health and can help detect a wide range of conditions, from anemia and infections to blood disorders.

The benzodiazepines urine test is a screening test that detects the presence of benzodiazepines and their metabolites (breakdown products) in your urine. Benzodiazepines are a class of prescription medications commonly used to treat anxiety, insomnia, muscle spasms, and seizure disorders. Examples include diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), and clonazepam (Klonopin).

The test is performed by drawing a small sample of blood, usually from a vein in your arm. A healthcare provider will clean the site with an antiseptic, wrap a band around your upper arm to make the vein easier to see, and insert a thin needle to collect the blood into a tube. The sample is then sent to a laboratory for analysis, and the entire process typically takes only a few minutes.

A urine sample is collected in a sterile container. You may be asked to provide a 'clean catch' sample to avoid contamination. The sample is then sent to a laboratory where it is analyzed using immunoassay techniques or gas chromatography-mass spectrometry to detect benzodiazepines or their metabolites.

Your doctor may order this test as part of a routine checkup, to look into symptoms such as fatigue, weakness, fever, unexplained bruising, or bleeding, or to monitor a condition you already have, such as anemia, an infection, or a blood disorder. It can also be used to see how well a treatment is working or to check for side effects of certain medications.

Your healthcare provider may order this test for several reasons: to monitor if you are taking your prescribed benzodiazepine medication as directed, to check for unauthorized use of benzodiazepines, as part of a routine drug screening (such as before surgery or for employment), or to help diagnose potential benzodiazepine overdose or poisoning.

In most cases, no special preparation is needed for a CBC. You can usually eat and drink normally beforehand unless your doctor tells you otherwise, especially if other blood tests that require fasting are being done at the same time. Be sure to tell your provider about any medications, vitamins, or supplements you are taking, and let them know if you have ever felt faint during a blood draw.

Generally, no special preparation is needed for a urine test. However, it is important to inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking, as some substances may affect the test results. Certain antibiotics, antidepressants, and other medications may cause false positive results.

Reference range

Negative. Cutoff concentration typically 200 ng/mL (screening) or 100 ng/mL (confirmation). Positive result indicates presence of benzodiazepines or their metabolites at or above the established cutoff.N/A

Specimen: urine

No special preparation required. Patient should be informed that certain prescribed medications (e.g., alprazolam, diazepam, lorazepam, clonazepam) will produce a positive result. Patients should disclose all current medications and supplements prior to testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates that benzodiazepines or their metabolites were detected in your urine. This could mean you have taken a prescribed benzodiazepine medication within the past few days, as these drugs can typically be detected in urine for several days after use, depending on the specific drug and your metabolism. A negative result suggests no detectable benzodiazepines were present at the time of testing, but this does not necessarily rule out their use if the medication has already been eliminated from your body. Your healthcare provider will interpret the results in the context of your medical history, symptoms, and prescribed medications.

Frequently asked questions

How long do benzodiazepines stay in urine?
The detection window varies depending on the specific benzodiazepine, the dose, frequency of use, and individual factors like metabolism and kidney function. Generally, benzodiazepines can be detected in urine for 1-7 days after last use. Long-acting benzodiazepines like diazepam may be detectable longer than short-acting ones like alprazolam.
Can a positive result occur from my prescribed medication?
Yes, if you are legitimately prescribed a benzodiazepine medication, it will likely show positive on this test. This is often the intended purpose of the test - to confirm you are taking your prescribed medication. Make sure to inform the testing facility and your healthcare provider about all prescription medications you are taking.
Can the test give false results?
Yes, false results can occur. Certain medications and supplements may cause false positive results, including some antidepressants, antibiotics, and herbal products. False negatives can occur if the test is performed too long after the last dose of medication. If results are unexpected, your doctor may order additional confirmatory testing.
Will a positive result show which specific benzodiazepine I took?
Standard screening tests may not identify the specific benzodiazepine. If more detailed information is needed, confirmatory testing using more advanced methods like gas chromatography-mass spectrometry can identify individual benzodiazepines and their exact levels.
Is the test painful?
No, providing a urine sample is painless. You simply urinate into a collection container. The test itself is performed on the sample in a laboratory.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy