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Complete Blood Count (CBC) Test: What It Measures and When Your Doctor May Order It

Published: August 9, 2026Updated: August 16, 2026

A screening test to detect the presence of benzodiazepines (sedative medications) in your blood.

Quick summary

{"This test checks for benzodiazepine drugs like Valium, Xanax, or Ativan in your blood","It uses a 200 ng/mL cutoff to determine if the result is positive or negative","The test is commonly used for monitoring medication compliance or checking for overdose","A positive result means benzodiazepines were detected above the threshold","Results are typically available within a few days"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78808-3
Short code
BENZ200
Synonyms
Benzodiaz SerPl Ql Scn>200 ng/mL
Category
chemistry
Sample
serum
Container
Red top (serum) or plasma separator tube (PST)
Units
N/A
Ref high
200
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen-ng-ml
CPT
80307
SNOMED
102088007
Specimen volume
1 mL
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

A complete blood count, commonly called a CBC, is a routine blood test that measures the cells circulating in your blood, including red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. These measurements help your healthcare provider evaluate your overall health and screen for a wide range of conditions.

This test looks for benzodiazepines in your blood. Benzodiazepines are a class of prescription medications commonly used to treat anxiety, insomnia, seizures, and muscle spasms. Common examples include diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), and clonazepam (Klonopin). The test uses a screening method with a cutoff of 200 ng/mL, meaning if the level detected is above this threshold, the result is considered positive.

Your doctor may order this test as part of a routine checkup, to investigate symptoms such as fatigue, weakness, fever, unexplained bruising, or unusual bleeding, or to monitor an existing condition such as anemia, infection, or a blood disorder. It is also used to track how treatments like chemotherapy or certain medications are affecting your blood cells.

Your healthcare provider may order this test for several reasons: to monitor if you are taking your prescribed medication as directed (compliance testing), to check for accidental or intentional overdose, to evaluate unexplained symptoms of sedation or confusion, or as part of a broader drug screening panel. It may also be used in emergency settings when a patient presents with symptoms of drug overdose.

The test is performed with a simple blood draw. A healthcare professional will clean the skin on the inside of your elbow, wrap a band around your upper arm, and insert a small needle into a vein to collect a sample into a tube. The procedure usually takes only a few minutes and may cause a brief sting. Pressure and a small bandage are applied afterward, and you can typically return to your normal activities right away.

A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood sample will be collected in a tube and sent to a laboratory for analysis. The test is a screening test, which means it provides a preliminary result. If the initial screen is positive, confirmatory testing may be performed to identify the specific benzodiazepine present.

Your results are reported as numbers compared against reference ranges, and each component tells a different story: red blood cell values can reveal anemia, white blood cell counts may point to infection or inflammation, and platelet levels relate to clotting. Values slightly outside the normal range do not always mean something is wrong, so your provider will interpret them together with your symptoms, medical history, and other test results before recommending any follow-up.

Results are reported as either positive or negative based on the 200 ng/mL cutoff threshold. A negative result means no benzodiazepines were detected, or the level was below the detection threshold. A positive result indicates that benzodiazepines were found in your blood above the cutoff level. However, this test does not indicate the specific amount taken, when it was taken, or whether the level is dangerous. Your healthcare provider will interpret the results in the context of your medical history and symptoms.

Reference range

Negative (Cutoff: 200 ng/mL)N/A

Specimen: serum

No special patient preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Benzodiazepines are central nervous system depressants that can cause drowsiness, confusion, impaired coordination, and in severe cases, respiratory depression. This test helps healthcare providers identify benzodiazepine use or overdose, which is important for proper treatment. Benzodiazepines have a high potential for dependence and abuse, making monitoring important for patient safety. The test may also help differentiate between benzodiazepine overdose and other causes of sedation. In treatment settings, this test ensures patients are taking their prescribed medications as directed.

Frequently asked questions

Will a positive result show which specific medication I took?
This is a screening test that detects the general presence of benzodiazepines. If needed, confirmatory testing can identify the specific benzodiazepine compound. Ask your healthcare provider if they ordered additional confirmatory testing.
How long do benzodiazepines stay in blood?
Benzodiazepines can typically be detected in blood for 24-72 hours after use, depending on the specific medication, dosage, and individual factors like metabolism. Longer-acting benzodiazepines like diazepam may be detectable longer than shorter-acting ones like alprazolam.
Can the test be wrong?
While rare, false positive results can occur due to interference from other substances. False negatives can occur if the sample is collected too long after use or if the level is below the detection threshold. Always discuss your results with your healthcare provider.
Do I need to fast before this test?
No fasting is typically required for this blood test. However, follow any specific instructions provided by your healthcare provider or the testing facility.
Is this test the same as a workplace drug test?
This test uses blood, while many workplace drug tests use urine. Blood tests generally detect more recent drug use. Your employer or testing facility will determine which type of test is appropriate.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy