Beta2gammaglobmfrurelph
This test separates and measures different types of proteins in urine to help diagnose kidney disorders and diseases affecting the immune system.
{"Measures beta 2 and gamma globulin proteins in urine","Helps diagnose kidney disease and immune system disorders","Involves analyzing urine sample through an electric field","Results show patterns that indicate specific health conditions","Often used with blood tests for complete evaluation"}
Key facts at a glance
- LOINC
- 54357-9
- Short code
- UB2GG
- Synonyms
- Beta2+Gamma Glob MFr Ur Elph
- Category
- chemistry
- Sample
- urine
- Container
- Sterile, screw-capped urine container (24-hour collection preferred); sterile random urine container acceptable
- Units
- N/A
- Ref low
- 0.2
- Ref high
- 0.5
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- CPT
- 84166
- SNOMED
- 104059005
- Specimen volume
- 10 mL aliquot from 24-hour collection (minimum 5 mL); complete 24-hour collection volume recorded
- Stability
- Refrigerated (2-8°C): 7 days; Frozen (-20°C): 1 month; Ambient temperature: 2 hours. Add thymol or toluene preservative for 24-hour collections if not refrigerated.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 24–72 hours
- Order
- routine
What is this test?
Urine protein electrophoresis is a laboratory test that separates the different proteins in your urine using an electric field. This test specifically measures beta 2 globulin and gamma globulin relative to total protein. Beta 2 globulin includes proteins like beta-2 microglobulin, while gamma globulins are primarily antibodies (immunoglobulins) produced by your immune system. By analyzing the pattern of these proteins, doctors can identify abnormalities that might indicate kidney damage, infections, or diseases like multiple myeloma.
How is the test performed?
A urine sample is collected, typically as a random sample or a 24-hour urine collection. The sample is placed on a special gel or membrane, and an electric current is applied. This causes the proteins to separate based on their electrical charge and size. The separated proteins are then stained and analyzed to determine the amount and pattern of each protein type, including beta 2 and gamma globulins.
Why might I need this test?
Your doctor may order this test if you have symptoms such as unexplained swelling, foamy urine, fatigue, or recurrent infections. It is also used to monitor known conditions affecting the kidneys or immune system. The test helps distinguish between different types of protein loss in urine, which can indicate the location and severity of kidney damage.
Reference range
Beta-2 globulin: 0.2-0.5 g/24h (or 3-7% of total urinary protein); Gamma globulin: 0.1-0.3 g/24h (or 2-5% of total urinary protein). Combined beta-2 + gamma globulin typically <10% of total urine protein. Total urine protein: <150 mg/24h.N/A
No special preparation required. Patient should maintain normal hydration. Avoid strenuous exercise prior to collection. For 24-hour collection, instruct patient on proper collection technique including discarding the first morning void and collecting all subsequent voids including the next morning void.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Does this test require fasting?
How long does it take to get results?
Are there any risks to this test?
What do abnormal results mean?
Will I need other tests?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy