Beta2globurelphmcnc
A urine test that measures beta-2 globulin protein levels using electrophoresis to help detect kidney damage.
{"Measures beta-2 globulin protein in urine to assess kidney function","Helps detect early kidney damage, especially to the renal tubules","Results are reported as a ratio or concentration compared to urine total protein"}
Key facts at a glance
- LOINC
- 54354-6
- Short code
- UB2G
- Synonyms
- Beta2 Glob Ur Elph-mCnc
- Category
- chemistry
- Sample
- urine
- Container
- Sterile, leak-proof urine container; sterile conical tube for aliquots; no preservative required for electrophoresis if processed promptly
- Units
- N/A
- Ref low
- 0
- Ref high
- 0.1
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–999 years
- Method
- electrophoresis
- CPT
- 84165 (Protein electrophoresis, urine); 82570 (Creatinine, urine) for normalization
- SNOMED
- 104021004 |Protein measurement, urine|; 311681001 |Urine electrophoresis test|
- Specimen volume
- 10-50 mL random urine or complete 24-hour collection (minimum 10 mL)
- Stability
- Room temperature: 2 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 1 month. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 24–72 hours
- Order
- routine
What is this test?
The urine beta-2 globulin test measures the amount of beta-2 globulin proteins in your urine using a technique called electrophoresis. Beta-2 globulin is a group of proteins in your blood that includes substances like transferrin and complement proteins. When kidneys are healthy, they filter these proteins from the blood and reabsorb them back into the bloodstream. When kidney tubules are damaged, beta-2 globulin leaks into the urine.
Why do I need this test?
Your doctor may order this test to: check how well your kidneys are working, detect early kidney damage before it becomes serious, monitor kidney disease progression, evaluate kidney function if you have diabetes or high blood pressure, or assess if a kidney transplant is functioning properly.
How to prepare for the test
This test typically requires a urine sample. You may need to collect urine over a 24-hour period or provide a random urine sample. Follow your doctor's instructions about collection. Drink plenty of water unless otherwise directed. Avoid strenuous exercise before the test as it may affect protein levels.
Understanding your results
Results are usually reported as a percentage of total urine protein or as a concentration (mass/volume). Normal results show very little or no beta-2 globulin in urine. Elevated levels may indicate kidney tubule damage, chronic kidney disease, or other kidney problems. Your doctor will interpret your results based on your overall health and other test findings.
Reference range
Beta-2 globulin: 0-0.1 mg/dL (typically <1% of total urine protein); Total urine protein: <150 mg/24 hoursN/A
No special preparation required. Patient should maintain normal hydration unless instructed otherwise by physician. First morning void or 24-hour collection preferred.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Is this test painful?
How long does it take to get results?
What can affect my test results?
Do I need to fast before this test?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy