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IgM Antibody Test (Immunoglobulin M): What It Is, Why It's Ordered, and What Your Results May Mean

Published: August 9, 2026Updated: August 15, 2026

A blood test that detects IgM antibodies against Bacteroides fragilis bacteria to help diagnose recent or active infections.

Quick summary

{"Measures IgM antibodies in your blood to check for Bacteroides fragilis infection","IgM antibodies are typically the first antibodies your body produces in response to an infection","This test helps doctors determine if you have a current or recent infection","Results are usually reported as positive, negative, or in some cases, with a titer value"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
27905-9
Short code
BFRAGM
Synonyms
B fragilis IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube without anticoagulant
Units
N/A
Ref low
9
Ref high
11
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Enzyme-linked immunosorbent assay (ELISA) or Immunofluorescence assay (IFA)
CPT
86674
SNOMED
122450008
Specimen volume
1-2 mL serum (minimum 0.5 mL)
Stability
Stable for 24 hours at 2-8°C; for prolonged storage, freeze at -20°C or below for up to 30 days; avoid repeated freeze-thaw cycles
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
48–168 hours
Order
routine

What is the IgM antibody test, and why might my doctor recommend it to check for a recent or current infection?

The Bacteroides fragilis IgM Antibody test is a blood test that looks for IgM antibodies specifically targeting Bacteroides fragilis bacteria. Bacteroides fragilis is a type of bacteria that normally lives in your intestines (gut). While usually harmless, it can sometimes cause infections, particularly in the abdomen, skin, or other tissues, especially after surgery or in people with weakened immune systems.

What exactly are IgM antibodies, and what does it mean when they are detected in my blood sample?

IgM antibodies are the first type of antibodies your immune system produces when fighting a new infection. They typically appear within the first week or two after infection and then decrease over time. Finding IgM antibodies in your blood usually indicates a recent or current infection, as opposed to IgG antibodies which indicate a past infection or immunity.

How is the IgM antibody test performed, and what should I expect during the blood draw at the lab or clinic?

A healthcare professional will draw a small blood sample from a vein in your arm. The blood is then sent to a laboratory where technicians test it for the presence of IgM antibodies against Bacteroides fragilis. You may experience slight pain or bruising at the needle site, but this is typically minor.

Do I need to prepare in any special way before having the IgM antibody test done, such as fasting or adjusting medications?

Generally, no special preparation is needed for this test. You can eat and drink normally before having your blood drawn. However, always follow any specific instructions your doctor may give you.

Reference range

Negative: <9 U/mL; Equivocal: 9-11 U/mL; Positive: >11 U/mL (method-dependent; refer to reporting laboratory reference values)N/A

Specimen: serum

No fasting required. Specimen should be collected prior to initiation of antibiotic therapy when possible for accurate antibody detection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is primarily used to help diagnose infections caused by Bacteroides fragilis, such as intra-abdominal infections, soft tissue infections, or septicemia (blood infection). It can be particularly useful when other tests (like bacterial cultures) are negative or inconclusive. A positive IgM result suggests recent or active infection, helping doctors guide appropriate antibiotic treatment.

Frequently asked questions

What does a positive result mean?
A positive result means IgM antibodies against Bacteroides fragilis were detected in your blood. This suggests you may have a current or recent infection with this bacteria. Your doctor will interpret this result along with your symptoms, other test results, and clinical history to determine the appropriate treatment.
What does a negative result mean?
A negative result means no IgM antibodies against Bacteroides fragilis were detected. This could mean you do not have an infection, or that the infection is very recent and antibodies haven't developed yet. If you have symptoms but the test is negative, your doctor may recommend repeat testing or additional tests.
Is this test painful?
The test involves drawing blood from a vein, which may cause brief discomfort or a slight sting. Some people may experience minor bruising at the site. These effects are usually temporary and resolve quickly.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the laboratory. Your healthcare provider will contact you with the results or discuss them at a follow-up appointment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy