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Streptococcus throat culture with qualitative detection of group A Streptococcus (GAS) antibodies (e.g., anti-streptolysin O, ASO)

Published: August 9, 2026Updated: August 16, 2026

This test involves collecting a sample from your throat to check for bacteria that may cause strep throat. It also measures certain antibodies your body produces in response to these bacteria.

Quick summary

["Helps diagnose strep throat and assess immune response to bacterial infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
546-2
Short code
B-Hem Strep Throat Ql Cult
Synonyms
B-Hem Strep Throat Ql Cult
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test includes two parts: a throat culture to identify live bacteria (such as Group A Streptococcus) and antibody testing to detect immune system responses. The culture helps determine if bacteria are present, while the antibody test looks for signs of past or ongoing infection.

How the Test Works

A swab is taken from your throat to grow bacteria in a lab. Separately, blood or serum is tested for specific antibodies (like anti-streptolysin O) that your immune system makes when fighting Group A Streptococcus. These antibodies can indicate a history of infection.

Why It’s Done

Doctors may order this test if you have symptoms like sore throat, fever, or swollen lymph nodes, especially if strep throat is suspected. Antibody testing can help confirm past infection or monitor immune response.

What to Expect

You’ll have a quick throat swab, and blood may be drawn separately. Results from the culture take 24–48 hours, while antibody results may be available sooner. Follow-up may include antibiotics if bacteria are confirmed.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive culture results may guide treatment with antibiotics to stop bacterial spread. Antibody levels can help diagnose past infections, monitor immune function, or assess exposure risk. High antibody titers may indicate ongoing immune activity or recent infection.

Short name

Throat Culture for Group A Strep Antibody Screen

Frequently asked questions

How long does it take to get results?
Culture results typically arrive within 24–48 hours, while antibody results may be available sooner, often within 24 hours of testing.
Can I take antibiotics before getting tested?
Yes, but inform your doctor immediately if you start antibiotics. They may need to adjust testing or interpretation to avoid false results.
Does this test detect all types of strep throat?
No, this test specifically checks for Group A Streptococcus (GAS) bacteria and related antibodies. Other strep types (e.g., Group C/D) are not covered.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy