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Bilirubin, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of bilirubin in a patient sample. Bilirubin is a yellow pigment produced during the breakdown of red blood cells.

Quick summary

["The bilirubin test helps evaluate red blood cell breakdown, liver function, and bile drainage."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72925-1
Short code
Bilirub Amn-sCnc
Synonyms
Bilirub Amn-sCnc
Category
liver
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What is this test?

This test measures bilirubin in a patient sample. Bilirubin is formed when the body breaks down heme, the oxygen-carrying part of red blood cells.

Why might I need this test?

Your clinician may order this test to investigate jaundice, unexplained changes in liver tests, suspected bile duct blockage, or increased red blood cell breakdown.

How is the test performed?

A laboratory method is used to measure the concentration of bilirubin in the submitted sample. The result is compared with laboratory reference information and interpreted alongside your other test results.

How do I prepare for the test?

Follow any instructions provided by your clinician or laboratory. Fasting is often unnecessary, but tell your clinician if you are pregnant or may be pregnant because bilirubin measurements are used in newborn screening.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated bilirubin result may occur with increased red blood cell breakdown, liver cell injury, or impaired bile flow. The pattern of other liver tests and the presence of symptoms can help identify the cause. A bilirubin result should be interpreted by a healthcare professional rather than viewed on its own.

Short name

Bilirubin

Frequently asked questions

What does bilirubin measure?
It measures the concentration of bilirubin, a yellow pigment produced during red blood cell breakdown.
What can cause a high bilirubin result?
Common causes include increased red blood cell breakdown, liver disease, and blockage of bile drainage. Your clinician will interpret the result with your symptoms and other laboratory tests.
Does a high bilirubin result always mean there is liver damage?
No. High bilirubin can have several causes, including blood cell breakdown or bile duct obstruction, so additional testing may be needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy