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Bilirubin, Whole Blood — Analyte Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures bilirubin in whole blood to help evaluate jaundice, liver function, and possible red blood cell breakdown.

Quick summary

["An abnormal bilirubin result can reflect liver problems, increased red blood cell breakdown, or blocked bile flow."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
89872-6
Short code
Bilirub BldA-sCnc
Synonyms
Bilirub BldA-sCnc
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of bilirubin, a yellow pigment made when the body breaks down red blood cells, in a whole-blood sample. Bilirubin is processed by the liver and may contribute to yellowing of the skin or eyes called jaundice.

Why might I need this test?

A clinician may order this test to investigate jaundice, assess liver function, or evaluate possible hemolysis, which is the premature breakdown of red blood cells. It may also be used in certain newborn assessments.

How is the test performed?

A small blood sample is collected, usually by finger stick or venipuncture, and the bilirubin level is measured in the laboratory. The test name does not specify a particular measurement method.

How do I prepare for the test?

Fasting is usually not required for a bilirubin test, but follow any instructions from your clinician. Tell the healthcare team about medicines, recent blood transfusions, pregnancy, or a possible pregnancy.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Whole Blood Bilirubin

Frequently asked questions

What does a bilirubin test measure?
It measures bilirubin, a pigment produced as red blood cells are broken down. The liver normally processes bilirubin so it can be removed from the body.
Why is my skin or eyes yellow?
Yellowing can occur when bilirubin levels are elevated. A bilirubin test is often used to help determine whether jaundice is related to the liver, bile ducts, or blood cells.
Do I need to fast before this test?
Fasting is generally unnecessary, although your clinician may give specific preparation instructions. Other laboratory tests ordered at the same time may have different preparation requirements.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy