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Bilirubin, Whole Blood — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of bilirubin in whole blood. Bilirubin is a yellow pigment produced during the breakdown of red blood cells.

Quick summary

["A bilirubin blood test can help evaluate causes of jaundice and may provide information about the liver or red blood cell breakdown."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48624-1
Short code
Bilirub BldCo-mCnc
Synonyms
Bilirub BldCo-mCnc
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of bilirubin in whole blood. Bilirubin is a yellow pigment formed when the body breaks down old red blood cells.

Why might I need this test?

A clinician may order this test to help evaluate jaundice, liver-related problems, or increased red blood cell breakdown. It may be used alongside other laboratory tests.

How is the test performed?

A blood sample is collected, usually from a vein in your arm. The laboratory measures the bilirubin concentration in the sample using an appropriate analytical method.

How do I prepare for the test?

No special preparation is usually required for a routine bilirubin test. Follow any instructions from your clinician, and tell the laboratory if you are pregnant or taking medicines that may affect liver function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Bilirubin, Whole Blood

Frequently asked questions

What does a bilirubin test measure?
It measures bilirubin, a yellow pigment produced as the body breaks down old red blood cells.
Is this test the same as a serum bilirubin test?
No. This test is specified for whole blood, while serum bilirubin is measured in the liquid portion of blood after cells have been removed. Your clinician determines which test is appropriate.
Does a high bilirubin level always mean the liver is not working?
No. Elevated bilirubin can have several causes, including liver or bile duct problems and increased red blood cell breakdown, so it must be interpreted with other findings.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy