Skip to content

Bilirubin, Whole Blood — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of bilirubin in a whole blood sample to help assess bile pigment metabolism, liver function, and possible red blood cell breakdown.

Quick summary

["This blood test can help identify causes of jaundice and may be used to evaluate the liver or red blood cell breakdown."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47994-9
Short code
Bilirub BldCo-sCnc
Synonyms
Bilirub BldCo-sCnc
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Bilirubin is a yellow substance produced during the normal breakdown of red blood cells. It is processed by the liver and eventually removed from the body in bile.

Why might I need this test?

This test may be ordered to investigate jaundice, a yellowing of the skin or eyes, or to evaluate liver function. It may also be used when there is concern about increased red blood cell breakdown.

How is the test performed?

A blood sample is collected, and the laboratory measures the amount of bilirubin in the whole blood. The result is reported as a substance concentration.

How do I prepare for the test?

Fasting is usually not required for this test, but follow any instructions from your healthcare professional. Tell the laboratory if you are pregnant or have recently had a blood transfusion, as these factors may affect interpretation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Whole Blood Bilirubin

Frequently asked questions

What does a bilirubin test measure?
It measures the amount of bilirubin in blood. Bilirubin is a yellow pigment formed as older red blood cells are broken down and processed by the liver.
Why is bilirubin checked with other blood tests?
Bilirubin alone may not show the cause of an abnormal result. Liver enzymes and tests of blood cell breakdown are often used together to help distinguish liver or bile-flow problems from hemolysis.
Does a high bilirubin level always mean the liver is damaged?
No. Elevated bilirubin can also result from increased red blood cell breakdown, bile duct obstruction, or other conditions, so your healthcare professional will interpret it alongside your symptoms and other test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy