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Bilirubin, Whole Blood — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the concentration of bilirubin, a yellow pigment made when the body breaks down heme, in a whole-blood sample.

Quick summary

["The result helps assess bilirubin production and the liver's ability to process and excrete it."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
59828-4
Short code
Bilirub BldV-mCnc
Synonyms
Bilirub BldV-mCnc
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of bilirubin in whole blood. Bilirubin is a yellow pigment formed during the breakdown of heme, the iron-containing part of hemoglobin.

Why might I need this test?

A doctor may order this test to evaluate jaundice, changes in liver function, bile duct problems, or increased red blood cell breakdown. It may also be included as part of a broader liver or blood assessment.

How is the test performed?

A blood sample is collected by venipuncture, usually from a vein in the arm. The laboratory measures the bilirubin concentration in the sample using a validated analytical method.

How do I prepare for the test?

No special preparation is usually required for this test. Follow your doctor's or laboratory's instructions, especially if the test is ordered with other blood tests that may require fasting.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Blood bilirubin test

Frequently asked questions

What does a bilirubin blood test measure?
It measures the concentration of bilirubin in blood. Bilirubin is produced as the body breaks down heme and is mainly processed by the liver.
Does a high bilirubin result always mean the liver is damaged?
No. High bilirubin can also result from increased red blood cell breakdown or impaired bile drainage, so it must be interpreted with symptoms and other laboratory results.
Is fasting required for this test?
Fasting is not usually required by itself. Preparation may vary if your doctor ordered the bilirubin test together with other tests, so follow the specific instructions provided.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy