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Indirect Bilirubin, Whole Blood — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of unconjugated bilirubin in blood, which can help evaluate jaundice and, in newborns, the risk of significant bilirubin elevation.

Quick summary

["This blood test helps assess bilirubin related to red blood cell breakdown and jaundice."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
64082-1
Short code
Bilirub Indirect BldCo-mCnc
Synonyms
Bilirub Indirect BldCo-mCnc
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Indirect bilirubin, also called unconjugated bilirubin, is a form of bilirubin that has not yet been processed by the liver. This test measures its amount in a blood sample.

Why might I need this test?

This test may be ordered to help evaluate jaundice, especially in newborns. It is often reviewed with total bilirubin and direct bilirubin to help determine the likely cause of an elevated result.

How is the test performed?

A small blood sample is collected and analyzed in the laboratory. In newborns, the sample may be obtained with a heel stick, depending on the test order and local procedures.

How do I prepare for the test?

Special preparation is usually not required. Follow the instructions provided by your healthcare professional, particularly if the test is part of newborn or follow-up care.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Indirect Bilirubin

Frequently asked questions

What is the difference between indirect and direct bilirubin?
Indirect bilirubin has not yet been processed by the liver, while direct bilirubin has been processed and is present in bile. Measuring both can help clarify the cause of jaundice.
Why is this test important for newborns?
Newborns commonly have temporary increases in bilirubin. Measuring bilirubin helps clinicians determine whether the level requires additional monitoring or treatment.
Does an elevated result always mean there is a liver problem?
No. Elevated indirect bilirubin can also result from increased red blood cell breakdown or other non-liver causes, so it must be interpreted with the rest of the medical evaluation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy