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Bilirubin, Skin — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures bilirubin in the skin, usually with a noninvasive transcutaneous bilirubin device, to help assess jaundice.

Quick summary

["This test estimates bilirubin in the skin to help evaluate jaundice, especially in newborns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58941-6
Short code
Bilirub Skin-mCnc
Synonyms
Bilirub Skin-mCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
transcutaneous-meter
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of bilirubin in the skin. Bilirubin is a yellow pigment made when the body breaks down red blood cells, and a buildup can cause yellowing of the skin and eyes called jaundice.

Why might I need this test?

Skin bilirubin measurement may be used to screen for or monitor jaundice. It is especially useful in newborns and may help guide whether additional testing, such as a blood bilirubin test, is needed.

How is the test performed?

The test is commonly performed with a handheld transcutaneous bilirubin device that measures light through the skin. The procedure is noninvasive, and the exact procedure may vary by laboratory.

How do I prepare for the test?

No fasting or blood draw is usually required. Follow the clinician's instructions, and tell the care team if the measurement area has a rash, open skin, heavy sun tan, or recently applied products that could affect the reading.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Skin bilirubin

Frequently asked questions

Is this the same as a blood bilirubin test?
They both measure bilirubin-related information, but a skin test is a noninvasive estimate rather than a laboratory measurement from a blood sample. The results are interpreted together with other findings and may be confirmed with a blood test.
Does this test require a needle or blood sample?
Usually not. It is commonly performed by placing a small measuring device against the skin.
What does an elevated result mean?
An elevated result can indicate jaundice and may reflect increased red blood cell breakdown, liver conditions, or blocked bile flow. Your clinician will interpret the result in your medical context and decide whether further testing is needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy