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Bilirubin, Skin — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

A skin-based bilirubin measurement used to estimate bilirubin levels in the body, most often in newborns and infants.

Quick summary

["This test can help assess bilirubin levels and identify possible jaundice, but a blood test may be needed for confirmation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72898-0
Short code
Bilirub Skin-sCnc
Synonyms
Bilirub Skin-sCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
transcutaneous-meter
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of bilirubin in the skin. Bilirubin is a yellow pigment produced when the body breaks down red blood cells, and elevated levels can cause yellowing of the skin and eyes, called jaundice.

Why might I need this test?

Skin bilirubin measurement is most commonly used to evaluate newborns and infants for jaundice. It may also be used to monitor bilirubin levels when a blood test is not practical or as part of a broader assessment of liver function or blood-cell breakdown.

How is the test performed?

A small measuring device is usually placed against the skin to estimate bilirubin without a needle. The result may be compared with a blood bilirubin test because skin measurements can be affected by factors such as skin characteristics, device calibration, and the presence of other pigments.

How do I prepare for the test?

No fasting is usually required. Follow the clinician's instructions, and make sure the testing area is clean and dry; lotions, creams, jewelry, or other coverings may need to be removed before the measurement.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Skin bilirubin

Frequently asked questions

Does this test require a blood draw?
Usually not. A skin bilirubin test is generally performed with a noninvasive measuring device placed against the skin.
Can a skin bilirubin test replace a blood bilirubin test?
Not always. Skin measurements are useful for screening and monitoring, but a blood test may be needed when a more precise result or treatment decision is required.
What can cause a high bilirubin result?
High bilirubin can result from normal newborn adjustment, increased red blood cell breakdown, liver conditions, or blocked bile flow. A clinician interprets the result in the context of symptoms, age, medical history, and other tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy