Bromocresol Purple Protein Electrophoresis (Serum)
This test measures protein distribution in your blood using an electrophoresis technique with bromocresol purple dye. It helps assess the balance of proteins, including albumin and globulins, which can indicate conditions like liver disease, kidney problems, or immune disorders.
["This test helps doctors check protein levels in your blood for potential health issues."]
Key facts at a glance
- LOINC
- 26645-2
- Short code
- BKVAB
- Synonyms
- BKV Ab Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top vacutainer tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Enzyme Immunoassay (EIA) / Immunofluorescence Assay (IFA)
- CPT
- 86698
- SNOMED
- 121781000
- Specimen volume
- 1-2 mL of serum (minimum 0.5 mL)
- Stability
- Serum stable at room temperature for 8 hours; refrigerated (2-8°C) for 7 days; frozen at -20°C or below for up to 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 50
- TAT
- 24–72 hours
- Order
- routine
What Does This Test Measure?
The test separates proteins in your serum based on size and charge. Bromocresol purple dye binds to proteins, creating bands that reflect different protein types. Key proteins like albumin (responsible for maintaining blood pressure) and globulins (linked to immune function) are analyzed. The results show relative amounts of these proteins, which can be compared to a reference pattern.
Why Might Your Doctor Order This Test?
Your doctor may recommend this test if they suspect conditions affecting protein balance, such as liver disease (e.g., cirrhosis), kidney disease, or certain autoimmune disorders. It can also help monitor treatment progress or diagnose hidden protein abnormalities.
How Is This Test Performed?
A blood sample is drawn from a vein, usually in your arm. The serum portion is separated and placed in a gel medium. An electric current is applied, causing proteins to migrate toward the dye. After staining with bromocresol purple, the bands are analyzed for protein distribution.
What Are Common Results and Next Steps?
Results show protein bands that may appear shifted or altered compared to normal patterns. Abnormal patterns could suggest low albumin (e.g., liver/kidney issues) or high globulins (e.g., inflammation or immune disorders). Your doctor will discuss findings with you and may recommend further tests or treatments.
Reference range
Negative: No detectable BK virus antibodies. Positive: Antibodies to BK virus detected, indicating prior exposure or current infection.N/A
No special patient preparation required. Fasting is not necessary.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
BCP Protein Electrophoresis
Frequently asked questions
How often will I need this test?
What if my results are outside normal ranges?
Can I prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy