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Serum or plasma concentration of bile acids (total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bile acids in your blood, which helps assess liver function and bile flow. Bile acids are produced by the liver and stored in the gallbladder.

Quick summary

["Bile acids help digest fats and signal the liver to produce bile; abnormal levels may indicate liver or gallbladder issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105014-5
Short code
GES5PCR
Synonyms
blaGES-5 Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Sterile transport container or appropriate culture swab transport medium (e.g., Copan ESwab, Amies transport medium). Serum separator tube (SST) if serum specimen is used.
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
molgen
CPT
87798 (amplified probe technique, each organism) or 87150 (PCR for antimicrobial resistance gene)
SNOMED
122450008
Specimen volume
1-3 mL serum, or per institutional protocol for bacterial isolates and clinical specimens
Stability
Serum stable at 2-8°C for 7 days. Frozen at -20°C or below for long-term storage. Transport to laboratory within 2 hours of collection at room temperature or refrigerated conditions.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate liver disease, bile duct blockages, or other conditions affecting bile production or flow. It can also help diagnose or monitor conditions like cirrhosis, cholestasis, or bile acid malabsorption.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Wear a loose shirt for easy access.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the process is quick. The sample is sent to a lab for analysis of bile acid levels.

Possible Results and Next Steps

Results are compared to your baseline or clinical context. High levels may suggest liver or gallbladder problems, while low levels could indicate malabsorption or other metabolic issues. Your provider will discuss findings with you.

Reference range

Negative (blaGES-5 gene not detected). Positive indicates the presence of the blaGES-5 carbapenemase gene conferring resistance to carbapenem antibiotics.N/A

Specimen: serum

No fasting required. Specimen should be collected prior to initiation of antibiotic therapy when possible. For bacterial culture or molecular testing, follow standard aseptic collection techniques appropriate to the specimen source.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Bile Acids

Frequently asked questions

What causes bile acid levels to change?
Changes in bile acid levels can result from liver disease, gallbladder removal, certain medications, or metabolic disorders. Dietary factors (e.g., high-fat foods) and dehydration may also influence results.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your provider will contact you once they’re ready for discussion.
Can diet affect bile acid test results?
Yes, eating a high-fat meal before testing may temporarily alter bile acid levels. Follow your provider’s instructions for fasting or dietary adjustments if applicable.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy