Skip to content

Immunoassay for Immunoglobulin G (IgG) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps fight infections and is important for long-term immunity.

Quick summary

["IgG helps protect your body from infections and long-term illness."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105015-2
Short code
CRB-GIM1
Synonyms
blaGIM-1 Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Sterile, leak-proof container; bacterial isolate on appropriate transport media (e.g., Amies or Stuart transport medium); or appropriate swab in transport system (e.g., Copan ESwab)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
molgen
CPT
87150
SNOMED
443451000124104
Specimen volume
1-2 mL of clinical specimen or visible bacterial growth on solid transport medium; minimum 0.5 mL for liquid specimens
Stability
Room temperature: 2 hours; Refrigerated (2-8°C): 24 hours for primary specimens; Bacterial isolates stable at room temperature on appropriate media for up to 48 hours; Frozen (-70°C or below): extended storage for purified nucleic acids
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–72 hours
Order
routine

What Does IgG Serve in Your Body?

IgG is the most common type of antibody in your blood. It plays a key role in defending against bacteria and viruses, including those that cause chronic infections. IgG antibodies are also passed from a mother to her baby through breast milk, providing early protection.

Why Might Your Doctor Order This Test?

Your doctor may check your IgG levels if you have symptoms of a weakened immune system, such as frequent infections, slow wound healing, or unexplained fatigue. It can also be used to monitor conditions like certain autoimmune diseases, infections, or to assess immune response after vaccination.

When Might You Receive This Test?

IgG tests are often done as part of a routine blood test or when you have symptoms that suggest an immune system issue. They may also be checked periodically if you have a known condition affecting immunity.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or hand to draw blood. If you are on blood thinners, let your doctor know before the test.

Reference range

Negative (blaGIM-1 gene not detected)N/A

Specimen: serum

No special patient preparation required. Sample collection should be performed prior to initiation of antimicrobial therapy when possible. Standard infection control precautions must be observed during specimen collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgG Level

Frequently asked questions

How low or high IgG levels can indicate health issues?
Low IgG levels may suggest an immune deficiency, such as a congenital or acquired condition that affects antibody production. Very low levels can increase your risk of severe infections. High IgG levels might be seen in chronic infections, autoimmune diseases, or certain types of cancer.
What causes IgG levels to change?
IgG levels can change due to infections, immune system disorders, certain medications, or genetic factors. Conditions like HIV/AIDS, lupus, or chronic liver disease can also influence IgG levels.
Does diet affect IgG levels?
Diet can indirectly affect immune health, which may influence IgG levels. Eating a balanced diet rich in vitamins and minerals supports overall immune function, but IgG levels are primarily determined by your body’s immune response.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy