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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function check via blood waste product levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105019-4
Short code
NDM1PCR
Synonyms
blaNDM-1 Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Sterile transport container or flocked swab in transport medium (e.g., Copan eSwab, Amies transport medium). For serum: red-top or serum separator tube (SST) without anticoagulant.
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
molgen
CPT
87641
SNOMED
416925001
Specimen volume
1-2 mL of specimen (serum, plasma, or bacterial isolate). For swabs: one flocked swab in transport medium.
Stability
Room temperature: 24 hours. Refrigerated (2-8°C): 7 days. Frozen (-70°C or below): 30 days. For bacterial isolates on solid media: stable at room temperature for transport.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–48 hours
Order
routine

Why This Test Matters

Creatinine levels are a key indicator of kidney function. Your kidneys filter waste products from your blood, including creatinine. If your levels are higher than usual, it may suggest kidney problems or reduced kidney function.

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood draw or urine sample collected, depending on the type of test. If it’s a blood test, you might feel a slight pinch, but it usually takes only a few minutes.

Common Causes of Abnormal Results

Elevated creatinine levels can occur if your kidneys aren’t working as well as they should, often due to conditions like dehydration, kidney disease, or blockages in the urinary tract. Lower levels may indicate overhydration or overuse of diuretics.

When to Talk to Your Doctor

If you’ve been diagnosed with kidney disease, have symptoms like swelling, fatigue, or changes in urine, or if your doctor suspects kidney issues, this test may be part of your follow-up. Persistently high or low levels should be discussed with your healthcare provider.

Reference range

Negative (blaNDM-1 gene not detected). Result reported as Detected or Not Detected.N/A

Specimen: serum

No special patient preparation required. Specimen should be collected prior to administration of antimicrobial agents when clinically feasible. Follow standard infection control precautions during specimen collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine

Frequently asked questions

How often is this test done?
This test is often checked regularly if you have kidney disease, diabetes, or high blood pressure. It may also be part of routine check-ups for people at higher risk of kidney problems, such as those with a family history of kidney disease.
What does a 'normal' result mean?
A 'normal' result doesn’t mean your kidneys are perfectly healthy—it means your creatinine levels fall within the typical range for most healthy adults. Your doctor will consider your overall health and other test results to interpret the meaning.
Can diet or exercise affect this test?
Yes, diet and hydration can influence creatinine levels. Eating foods high in protein or drinking less water before the test might temporarily change your result. Your doctor may ask you to follow specific instructions, like avoiding certain foods or timing your test with your last meal.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy