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Total Protein in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum, which includes both albumin and globulin proteins essential for various bodily functions.

Quick summary

["Assesses overall protein levels in your blood for health monitoring and diagnosis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105029-3
Short code
OXA24
Synonyms
blaOXA24/40 gene Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Sterile transport container or bacterial culture transport medium
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
CPT
87798
SNOMED
398141002
Specimen volume
1-2 mL of serum or appropriate clinical specimen (blood, respiratory, urine, or tissue as clinically indicated)
Stability
Refrigerated (2-8°C) for up to 7 days; Frozen (-20°C or below) for up to 30 days; Room temperature for up to 24 hours
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate kidney function, detect liver disease, monitor nutritional status, or identify conditions like malnutrition, dehydration, or certain blood disorders. It can also help assess protein-losing conditions or track responses to treatments.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for 8–12 hours before the test if your provider specifies it, but this is not always required for protein measurement. Bring any medications or questions to your appointment.

What Happens During the Test?

A small sample of blood will be drawn from a vein in your arm by a healthcare professional. The blood is then sent to a lab for analysis. The process usually takes a few minutes, and you may experience slight discomfort or bruising at the site.

What Are the Results Mean?

Results help determine if your protein levels are within normal ranges. Abnormally low or high levels may signal underlying health issues that need further investigation, such as dietary deficiencies, organ dysfunction, or immune system disorders.

Reference range

Negative (blaOXA-24/40 gene not detected)N/A

Specimen: serum

No special patient preparation required. Sample should be collected prior to antibiotic administration when clinically possible to maximize detection sensitivity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low total protein levels may indicate conditions like malnutrition, kidney disease, or severe infections, while elevated levels could suggest dehydration, inflammation, or certain liver or kidney disorders. Regular monitoring is important for patients with chronic conditions like cirrhosis or nephrotic syndrome.

Short name

Total Serum Protein

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1–3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you with the final report once reviewed.
What does a low or high protein level mean?
A low protein level may signal poor nutrition, kidney problems, or chronic illness, while high levels could indicate dehydration, inflammation, or certain metabolic disorders. Your provider will discuss findings in detail with you.
Can diet affect my protein test results?
Dietary changes may influence protein levels, especially if you consume significantly more or less protein than usual. Avoid extreme dietary shifts before testing unless advised by your provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy