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C-reactive protein (CRP) by nephelometry (plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105030-1
Short code
OXA244
Synonyms
blaOXA-244 Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Sterile transport container or nucleic acid preservation tube; avoid containers with preservatives that may inhibit PCR
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
molgen
CPT
87798
SNOMED
415684004
Specimen volume
1-2 mL of serum or appropriate clinical specimen (e.g., rectal swab, urine, blood culture isolate)
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or lower): 30 days for nucleic acid preservation
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order CRP testing to check for signs of inflammation. This can help diagnose conditions like infections (e.g., pneumonia, urinary tract infections), autoimmune diseases (e.g., rheumatoid arthritis), or to monitor healing after procedures or injuries. It may also be used to evaluate risk for heart disease or to guide treatment decisions.

What Does a High or Low CRP Level Mean?

A high CRP level often indicates inflammation or infection. While a low level usually suggests no active inflammation, it doesn’t rule out all causes. Your provider will interpret results in the context of your overall health and symptoms.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The plasma is then analyzed using nephelometry, a method that measures how particles scatter light to detect CRP levels.

What Should You Do Before the Test?

Avoid strenuous exercise or extreme stress 24 hours before the test, as these can temporarily raise CRP levels. If you’re on medication, let your provider know, as some may affect results.

Reference range

Negative for blaOXA-244 gene (Target Not Detected). Result reported as Detected or Not Detected.N/A

Specimen: serum

No special patient preparation required. Collect specimen prior to administration of antimicrobial agents when possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (Plasma)

Frequently asked questions

Can CRP levels change with diet or exercise?
Diet and exercise can influence inflammation indirectly. For example, a healthy diet may reduce inflammation, but CRP results alone don’t reflect lifestyle changes. Your provider will consider other factors when interpreting results.
Is CRP testing painful?
The blood draw itself is usually mild discomfort, but most people tolerate it well. The process is quick, and any soreness fades shortly after.
How often should CRP be checked?
Frequency depends on your health needs. Your provider may recommend periodic checks if you have chronic conditions like heart disease or autoimmune disorders, or if you’re undergoing treatment requiring monitoring.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy