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C-reactive protein (CRP) by nephelometry (plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by your liver in response to inflammation or infection in your body.

Quick summary

["CRP helps track inflammation, often used to monitor conditions like infections, autoimmune diseases, or post-surgery healing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101126-1
Short code
OXA24-40
Synonyms
blaOXA-24+blaOXA-40 Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Sterile transport container or nucleic acid preservation tube (e.g., Copan ESwab, sterile screw-cap container, or molecular transport medium)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–99 years
Method
molgen
CPT
87798 (unlisted infectious agent detection by nucleic acid) or 87150 (PCR amplification with probe detection)
SNOMED
434831000124103
Specimen volume
1-2 mL of serum or appropriate clinical specimen (blood, respiratory, urine, or tissue per clinical indication)
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-70°C or below): 30 days. Transport to laboratory promptly.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a CRP test to check for signs of inflammation, monitor chronic conditions like arthritis or heart disease, or evaluate how your body is responding to an illness or treatment. It can also help determine if an infection is present or worsening.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood, which is then sent to the lab for analysis. If you’re on blood-thinning medication, let your provider know before the test.

What to Expect During the Test

The blood draw usually takes a few minutes. You might feel a slight pinch, but most people tolerate it well. If you’re anxious about needles, ask your provider about numbing cream or other options.

Possible Results and Next Steps

Higher-than-normal CRP levels may indicate inflammation, infection, or other health issues. Lower levels might suggest less inflammation. Your provider will discuss the results with you and decide if further testing or treatment is needed.

Reference range

Negative (blaOXA-24 and blaOXA-40 carbapenem resistance genes not detected)N/A

Specimen: serum

No special patient preparation required. Collect specimen prior to administration of antibiotics when clinically feasible to maximize detection sensitivity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP plays a key role in identifying and managing inflammatory conditions. It’s often used as a marker to assess risk for conditions like cardiovascular disease, rheumatoid arthritis, or sepsis. Elevated levels can prompt additional investigations or adjustments to treatment plans.

Short name

CRP (Nephelometry)

Frequently asked questions

What does a high CRP level mean?
A high CRP level often signals inflammation in your body, which could be due to infections, autoimmune diseases, or other health problems. Your provider will review the results with you to determine the best next steps, such as further testing or treatment adjustments.
How often should I get this test?
The frequency depends on your medical condition and why the test was ordered. Some people may need CRP tests regularly (e.g., every few months) to monitor chronic inflammation, while others may only need it once for a specific reason, like evaluating an infection or response to treatment.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. Eating a heart-healthy diet, staying active, and managing stress may help lower inflammation over time. Always follow your provider’s advice for managing your condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy