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C-reactive protein (CRP) by nephelometry (plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85503-1
Short code
OXA48
Synonyms
blaOXA-48 Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Sterile, leak-proof primary container; red-top serum tube or sterile transport container for serum specimen
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
molgen
CPT
87798
SNOMED
446240005
Specimen volume
1-2 mL of serum; minimum 0.5 mL
Stability
Room temperature: 2 hours; Refrigerated (2-8°C): 24 hours; Frozen (-70°C or below): 30 days for nucleic acid preservation. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for signs of inflammation, monitor chronic conditions like arthritis or heart disease, or evaluate responses to treatments. It can also help identify infections or other inflammatory processes in your body.

What Does a High or Low CRP Level Mean?

Elevated CRP levels often indicate inflammation or infection, but they can also be influenced by other factors like stress, certain medications, or obesity. Low levels may suggest reduced inflammation, but they don’t always mean you’re healthy.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. Plasma is separated from blood cells and sent to the lab for testing. This test is typically done on fresh plasma to ensure accurate results.

What to Expect Before the Test

No special preparation is needed for this test. You may eat and drink normally, but inform your doctor if you’re taking blood-thinning medications or have any bleeding disorders.

Reference range

Negative for blaOXA-48 gene (Not Detected). A positive result indicates the presence of the carbapenemase-producing blaOXA-48 resistance gene.N/A

Specimen: serum

No special patient preparation is required. Specimen should be collected prior to administration of antimicrobial therapy when possible, as antibiotic treatment may affect bacterial load and detection sensitivity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP Plasma

Frequently asked questions

How Long Does It Take to Get Results?
Results are usually available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I Eat or Drink Before This Test?
Yes, you can eat and drink normally before this test. Avoiding food or fluids isn’t necessary unless your doctor specifies otherwise.
Does This Test Require Special Dietary Restrictions?
No special dietary restrictions are needed for this test. However, if you’re on a specific diet (e.g., low-sodium, low-fat), let your doctor know to avoid any potential interference with results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy