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C-reactive protein (CRP) concentration in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a substance produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, which can signal infections, injuries, or other health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88248-0
Short code
OXA
Synonyms
blaOXA Bld Pos Ql Probe
Category
chemistry
Sample
whole-blood
Container
Positive blood culture bottle (aerobic or anaerobic) submitted in original manufacturer container; do not transfer to alternate tubes
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
probe
CPT
87150
SNOMED
122450008
Specimen volume
3-10 mL of blood per culture bottle set (pediatric: 1-3 mL); testing performed directly from positive flagged bottle
Stability
Process as soon as blood culture flags positive (ideally within 8 hours of positivity); stable at room temperature up to 24 hours post-positivity for molecular testing
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
1–4 hours
Order
routine

Why Is This Test Done?

Doctors may order CRP testing to check for signs of inflammation, monitor conditions like arthritis, heart disease, or infections, or evaluate responses to treatments. It can also help assess risk for certain conditions before they become severe.

What to Expect During the Test

A blood sample is taken from a vein, usually in your arm. You may feel a small pinch when the needle is inserted, but the process is quick. No special preparation is needed unless your doctor instructs otherwise.

Common Conditions Monitored

High CRP levels may indicate infections (like pneumonia or sepsis), autoimmune diseases (such as rheumatoid arthritis), heart problems, or other inflammatory conditions. Low levels might suggest no active inflammation, but this can vary based on individual health.

What the Results Mean

Results are interpreted by your healthcare provider based on your overall health, symptoms, and medical history. Elevated CRP levels often prompt further investigation, while normal levels do not rule out inflammation entirely.

Reference range

Detected / Not detected (qualitative); Negative (no blaOXA carbapenemase gene detected) is the expected reference resultN/A

Specimen: whole-blood

No special patient preparation required; specimen is collected from positive blood culture bottles flagged by continuous-monitoring blood culture systems

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (Plasma)

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition and treatment plan. Your doctor will determine how often you need CRP testing, whether it’s once, periodically, or as part of ongoing monitoring.
Can lifestyle changes affect CRP levels?
Yes, lifestyle factors like diet, exercise, and smoking can influence inflammation. Reducing inflammation through healthy habits may lower CRP levels, but results vary by individual. Always follow your doctor’s advice.
Is CRP testing painful or uncomfortable?
Most people experience only mild discomfort during blood drawing, which usually resolves quickly. If you have a fear of needles, let your doctor know so they can discuss alternatives or reassurance techniques.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy