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Blast Cells, CD45, Nonfractionated Whole Blood — Flow Cytometry

Published: August 9, 2026Updated: August 17, 2026

A flow-cytometry blood test that identifies and counts blast cells (immature blood cells), using the CD45 cell marker.

Quick summary

["This test measures immature blood cells in a blood sample and can help evaluate suspected blood cancers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
107078-8
Short code
Blasts.CD45 NFr Bld FC
Synonyms
Blasts.CD45 NFr Bld FC
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
84484
SNOMED
302774002
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures blast cells, which are immature blood cells that have not yet fully matured. Flow cytometry uses fluorescent markers, including CD45, to help identify and count these cells in whole blood.

Why might I need this test?

It may be ordered when a blood count is abnormal or when a clinician is evaluating a possible leukemia, lymphoma, or another blood-cell disorder. It can also be used to monitor certain cancers or treatment-related changes.

How is the test performed?

A blood sample is analyzed with flow cytometry, which measures light emitted by labeled cells. The laboratory examines the cells' characteristics, including CD45 expression, to identify and estimate the number of blasts.

How do I prepare for the test?

No special preparation is usually required. Follow the laboratory's instructions, and tell your clinician if you have recently received chemotherapy, stem-cell transplantation, or other treatment that could affect blood-cell findings.

Reference range

Adult: 10-40 U/LN/A

Specimen: whole-blood

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An increased number or abnormal pattern of blast cells may occur with leukemia, lymphoma, marrow disorders, or recovery after intensive treatment. Flow cytometry provides information about the cells' markers but usually must be interpreted with the blood count, symptoms, examination, and sometimes a bone marrow biopsy. A low or absent blast count does not by itself rule out a blood disorder.

Short name

Blast cell count

Frequently asked questions

What are blast cells?
Blasts are immature blood cells produced in the bone marrow. Normally, most blasts mature before entering the bloodstream.
Does this test diagnose cancer by itself?
No. It can identify and characterize abnormal blast cells, but a cancer diagnosis generally requires additional laboratory findings and clinical evaluation.
Why is CD45 included in the test name?
CD45 is a marker found on many white blood cells. Evaluating CD45 helps flow cytometry distinguish and classify immature white blood cells.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy