Blast Cell Score, CD45, Nonfractionated Specimen — Flow Cytometry
A flow cytometry test that estimates the proportion of immature blast cells using CD45 staining in a nonfractionated specimen.
["This test helps assess the number and characteristics of immature blood cells, often in the evaluation or monitoring of leukemia."]
Key facts at a glance
- LOINC
- 107076-2
- Short code
- Blasts.CD45 NFr Spec FC
- Synonyms
- Blasts.CD45 NFr Spec FC
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 84484
- SNOMED
- 302774002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test uses flow cytometry to estimate the blast cell score, which is the proportion of immature precursor cells in the submitted sample. CD45 is a cell-surface marker commonly used to help identify and classify white blood cells.
Why might I need this test?
A blast cell score may be ordered when leukemia or another blood-forming disorder is suspected. It may also be used to monitor response to treatment or assess changes after bone marrow transplantation.
How is the test performed?
A laboratory instrument called a flow cytometer analyzes individual cells after they are stained with fluorescent antibodies, including CD45. The laboratory then estimates the percentage of cells with characteristics of blasts.
How do I prepare for the test?
Special preparation such as fasting is generally not required for a blood flow cytometry test. If the order includes a bone marrow sample, the collection is performed by a healthcare professional, and you should follow the instructions provided by your care team.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An increased blast cell score may occur with acute leukemia, certain other blood disorders, or during recovery after marrow-damaging treatment. Results must be interpreted with the overall cell count, blood or marrow findings, other flow cytometry markers, and your treatment history; there is no single cutoff that applies to every patient.
Short name
CD45 blast cell score
Frequently asked questions
Does a high blast cell score always mean I have leukemia?
What is CD45?
Does this test replace a bone marrow biopsy?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy