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Blast Cell Number Fraction, Bone Marrow — Flow Cytometry

Published: August 9, 2026Updated: August 16, 2026

A flow cytometry test that measures the proportion of blast cells in a bone marrow sample and helps characterize their cell-surface markers.

Quick summary

["This test measures immature blood-forming cells in bone marrow to help evaluate and monitor blood cancers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107055-6
Short code
Blasts.HLA-DR+ NFr Mar FC
Synonyms
Blasts.HLA-DR+ NFr Mar FC
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
0.1 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Blast cells are immature blood-forming cells that normally develop into mature blood cells. This test measures their proportion in bone marrow and uses flow cytometry to examine their cell-surface characteristics.

Why might I need this test?

The test may be used to investigate unexplained blood-count abnormalities, evaluate suspected leukemia or lymphoma, classify blood cancers, and monitor response to treatment. It is often performed with other bone marrow, blood, and genetic tests.

How is the test performed?

A clinician removes a small amount of liquid bone marrow, usually with a needle. The laboratory analyzes the cells using flow cytometry, which identifies cells based on specific markers; a bone marrow biopsy may also be collected for tissue examination.

How do I prepare for the test?

There is usually no fasting requirement, but follow the clinic's instructions about medicines, blood thinners, allergies, and sedation or local anesthetic. Contact the healthcare team before the procedure if you have concerns about bleeding or medication use.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An increased proportion of blast cells may occur in acute leukemia and other disorders of blood-cell production. Flow cytometry can also help identify the type of blast cells. Results must be interpreted with blood counts, bone marrow findings, genetic testing, and the clinical picture because an abnormal result alone does not establish a diagnosis.

Short name

Bone Marrow Blast Percentage

Frequently asked questions

What are blast cells?
Blast cells are immature blood-forming cells. A small number can normally be present in bone marrow, while a larger proportion may indicate abnormal blood-cell development.
Does an abnormal result mean I have leukemia?
Not necessarily. An increased blast proportion can occur with leukemia, but it may also have other causes, so the result must be interpreted along with the rest of the evaluation.
Is this the same as a bone marrow biopsy?
No. Flow cytometry analyzes individual cells from a bone marrow sample, while a biopsy examines a small piece of marrow tissue under a microscope. Both procedures may be performed during the same visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy