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Bilirubin, Total (Serum or Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps the liver process waste products.

Quick summary

["Bilirubin helps diagnose liver and bile duct conditions, including jaundice and gallbladder issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85830-8
Short code
VIMPCR
Synonyms
blaVIM Islt Ql NAA+probe
Category
chemistry
Sample
serum
Container
Sterile, leak-proof container (serum separator tube for serum)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
87798
SNOMED
445451000124102
Specimen volume
1-2 mL serum
Stability
Room temperature: 2 hours; Refrigerated (2-8°C): 24 hours; Frozen (-70°C or below): 7 days
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Bilirubin is a key indicator of liver function and bile flow. High levels can signal problems like jaundice (yellowing of skin/eyes), liver disease, or blockages in the bile ducts. Low levels may suggest certain blood disorders or liver damage.

What to Expect Before the Test

No special preparation is needed. You may drink water if thirsty, but avoid eating or drinking anything for 8–12 hours before the draw. Wear a loose shirt for easy access to your arm.

What Happens During the Test

A healthcare provider will insert a small needle into a vein in your arm to draw a blood sample. You may feel a brief pinch, but it usually doesn’t cause discomfort. The process takes about 5 minutes.

What the Results Mean

Results are compared to a reference range specific to your age, sex, and overall health. Elevated bilirubin may require further testing (e.g., liver enzymes, ultrasound) to pinpoint the cause. Your doctor will discuss findings with you.

Reference range

Negative (blaVIM gene not detected)N/A

Specimen: serum

No special patient preparation required. Collect specimen prior to initiation of antimicrobial therapy when possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Bilirubin

Frequently asked questions

What causes elevated bilirubin?
Elevated bilirubin often results from conditions like hemolysis (red blood cell breakdown), liver disease (e.g., hepatitis, cirrhosis), or bile duct obstructions (e.g., gallstones). It can also appear in newborns due to immature liver function.
What causes low bilirubin?
Low bilirubin is less common but may occur in conditions like severe anemia, liver disease, or certain medications. It can also be a normal variant in some individuals.
How often should I get this test?
Your doctor will determine frequency based on your health history and symptoms. Regular monitoring may be needed if you have liver disease, bile duct issues, or other conditions affecting bilirubin levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy