Complete Blood Count with Differential (CBC with Differential)
This test measures your blood’s overall health, including red blood cells, white blood cells, and platelets, along with the proportions of different types of white blood cells.
["A CBC helps diagnose and monitor conditions like anemia, infections, or blood disorders."]
Key facts at a glance
- LOINC
- 4490-9
- Short code
- C3b-C4b Recep EntNum RBC
- Synonyms
- C3b-C4b Recep EntNum RBC
- Category
- coagulation
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Does the CBC Measure?
Your blood is analyzed for several key components: **Red Blood Cells (RBCs)** – carry oxygen to your body’s tissues; **White Blood Cells (WBCs)** – fight infections and inflammation; and **Platelets** – help your blood clot. The differential count breaks down the types of white blood cells (neutrophils, lymphocytes, monocytes, eosinophils, basophils) to identify specific health concerns.
Why Might You Need This Test?
A CBC is often the first test doctors use to check for signs of anemia, infections, bleeding disorders, or other blood-related issues. It can also help monitor chronic conditions like diabetes, kidney disease, or cancer.
How Is the Test Performed?
A small blood sample is taken from your arm or finger. The blood is then examined under a microscope to count and identify the different cell types. Some labs may use automated machines to analyze the sample quickly and accurately.
What Are Common Results and Their Meanings?
Low RBCs or hemoglobin may indicate anemia, while high RBCs could suggest dehydration or other conditions. Low platelets may signal bleeding disorders, and high platelet counts might point to conditions like cancer or infection. The differential helps pinpoint whether an infection is viral, bacterial, or another type.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CBC with Differential
Frequently asked questions
What Are the Normal Values for This Test?
How Long Does It Take to Get Results?
Can I Eat or Drink Before This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy