Complete Blood Count with Differential (CBC with Differential)
This test measures your blood’s overall health, including red blood cells, white blood cells, and platelets, along with the proportions of different types of white blood cells.
["A CBC helps doctors diagnose and monitor conditions like anemia, infections, or blood disorders."]
Key facts at a glance
- LOINC
- 6296-8
- Short code
- C3b-C4b Recep RBC Ql
- Synonyms
- C3b-C4b Recep RBC Ql
- Category
- coagulation
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Does a CBC Measure?
A CBC evaluates several key components of your blood: - **Red blood cells (RBCs):** Carry oxygen to tissues. - **Hemoglobin:** The protein in RBCs that transports oxygen. - **Hematocrit:** The percentage of blood volume made up of RBCs. - **Platelets:** Help with blood clotting. - **White blood cells (WBCs):** Fight infections and inflammation. - **Differential count:** The breakdown of WBC types (e.g., neutrophils, lymphocytes).
Why Might You Need a CBC?
Doctors order a CBC to check for signs of: - Anemia (low RBCs or hemoglobin). - Infections (e.g., high WBCs). - Blood disorders (e.g., leukemia, thrombocytopenia). - Kidney or liver issues (indirectly, through RBC/protein levels).
How Is a CBC Performed?
A small blood sample is drawn from a vein (usually in your arm). The sample is sent to a lab, where machines analyze it for RBCs, WBCs, platelets, and their proportions. No special preparation is needed, but fasting isn’t required for this test alone.
What Are Common Results?
Results may show: - **Low RBCs/hemoglobin:** Possible anemia. - **High WBCs:** Possible infection or inflammation. - **Low platelets:** Risk of bleeding. - **Abnormal WBC differential:** Could signal immune issues or other conditions.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CBC with Differential
Frequently asked questions
How often do I need a CBC?
Can I prepare for a CBC?
Does a CBC hurt?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy